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OG0-061 IT4IT Part 1

Exam Name: IT4IT Part 1 Exam

Exam Number: OG0-061 - English

Qualification upon passing: IT4IT Foundation (and partial credit towards a future Level 2 qualification)

Delivered at: Authorized Examination Provider Test Centers and also available as an Online Proctored exam.

Prerequisites: None

Supervised: Yes

Open Book: No

Exam type: Simple Multiple choice

Number of questions: 40

Pass score: 65% (26 out of 40 questions)

Time limit: 60 minutes (*)

Retake policy: If you fail the test you must wait one month before another attempt



The Open Group Certification for People: IT4IT Certification Program (the Program) makes certification available to people who demonstrate knowledge and understanding of the IT4IT Body of Knowledge. The Program also provides accreditation for training courses designed to help people acquire the necessary knowledge and understanding of the Body of Knowledge in order for the person to achieve certification.


IT4IT Part 1
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OG0-061 IT4IT Part 1
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OGBA-101 TOGAF Business Architecture Foundation
OGEA-103 TOGAF Enterprise Architecture Combined Part 1 and Part 2

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Question #35 Section 1
What are the typical activities of the Strategy to Portfolio Value Stream?
A. Strategy, Service Portfolio, Demand, Selection
B. Strategy, Enterprise Architecture, Portfolio, Release
C. Strategy, Finance, Service Level Management, Investment Portfolio
D. Strategy, Release, Change, Investment Policy
Answer: A
Reference:
https://books.google.com.pk/books?id=lOoCDQAAQBAJ&pg=PA130&lpg=PA130&dq=IT4IT+typical+activities+of+the+Strategy+to+Portfolio+Value
+Stream+Strategy,+Service+Portfolio,+Demand,
+Selection&source=bl&ots=KwfVdFuBL3&sig=ACfU3U2uzbzi8_xyJfw537s2REQ3l1MCKw&hl=en&sa=X&ved=2ahUKEwi0zeq35OjkAhVNURoKHTu2DgkQ6AEw
BnoECAkQAQ#v=onepage&q=IT4IT%20typical%20activities%20of%20the%20Strategy%20to%20Portfolio%20Value%20Stream%20Strategy%2C%20Service%
20Portfolio%2C%20Demand%2C%20Selection&f=false
Question #36 Section 1
What does the IT4IT Information Model consist of?
A. The Service Model and the Service Backbone
B. Value streams and functional components
C. Data objects and their relationships
D. Capabilities and IT processes
Answer: C
Reference:
https://pubs.opengroup.org/it4it/refarch20/chap03.html
Question #37 Section 1
What data object is associated with the Engagement Experience Portal?
A. Shopping Cart
B. Service Catalog Entry
C. User Profile
D. Offer
Answer: D
Reference:
https://pubs.opengroup.org/it4it/refarch20/m/chap07.html
Question #38 Section 1
What is an objective of the Detect to Correct value stream?
A. To build a culture of collaboration between IT operations and IT development
B. To manage an inviting consumption experience to acquire services, goods, knowledge, and support
C. To track the service usage and control the chargeback contract
D. To provide an overview of the business of IT operations and the services delivered
Answer: D
Reference:
https://pubs.opengroup.org/it4it/refarch20/chap08.html
Question #39 Section 1
Which of the following best describes The Open Group IT4IT Reference Architecture?
A. A policy framework for IT governance
B. A supply chain management model
C. A technical interoperability standard
D. A standard for managing the business of IT
Answer: D
Reference:
https://pubs.opengroup.org/it4it/refarch21/IT4ITv2.1.html
Question #40 Section 1
Which value stream connects consumers with IT goods and services?
A. Detect to Correct
B. Strategy to Portfolio
C. Request to Fulfill
D. Requirement to Deploy
Answer: C
Reference:
https://pubs.opengroup.org/it4it/refarch20/chap03.html
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The-Open-Group IT4IT study help - BingNews https://killexams.com/pass4sure/exam-detail/OG0-061 Search results The-Open-Group IT4IT study help - BingNews https://killexams.com/pass4sure/exam-detail/OG0-061 https://killexams.com/exam_list/The-Open-Group The Deals: WMG to Help Study ‘Music as Medicine'; Secretly to Distribute for Madlib, David Gray & More No result found, try new keyword!Warner Music Group has partnered with British health tech start-up MediMusic to trial "music as medicine" to help relieve pain, anxiety and stress. MediMusic will conduct research testing in ... Wed, 13 Dec 2023 10:01:00 -0600 en-us text/html https://www.msn.com/ New Study: How Tonsillectomy Can Help Behavior Of Children Who Snore

A study published in this month’s Journal of the American Medical Association, or JAMA, found that tonsil and adenoid surgery in children with sleep difficulties due to snoring may help them with daytime issues such as behavior challenges and overall quality-of-life. The study was a randomized clinical trial of over 400 children with large tonsils and adenoids causing snoring and breathing issues during sleep.

The investigators randomly assigned half of the children with these issues to have their tonsils and adenoids removed, and the other half to undergo ‘watchful waiting’ over a 12 month period. The study group, based out of multiple institutions in the U.S., evaluated several metrics of behavior and quality-of-life both before study enrollment and 12 months later. The study format was approved by institutional review boards at each of the investigation treatment sites.

The two groups of children, with an average age of six years, were assessed before study enrollment and 12 months later for improvement in behavior, focus, executive function and quality-of-life. Those who had their tonsils and adenoids removed were found to have improved quality-of-life, which was analyzed in parental questionnaire format based on standardized pediatric quality-of-life measuring tools, as well as improved behavior, also based on standardized measuring parameters, compared with those who did not undergo tonsillectomy and adenoidectomy surgery. However, the investigators found no difference between groups when measuring for changes in executive function and attention.

As is well documented, children who have sleep issues due to snoring, known as sleep disordered breathing, can have problematic daytime behaviors including focus issues and learning challenges. Snoring and mild sleep apnea disrupt sleep cycles and depth of sleep in both children and adults, whereby what seems like a full night’s sleep may be functionally just half a night’s sleep if the sleep quality is poor. Some children who snore have issues of sleepiness, but it’s actually more common for sleep-deprived kids to be ‘tired and wired.’ Many of these children have been over-diagnosed with attention deficit hyperactivity disorder, or ADHD.

Dr. Ron Mitchell, Professor of Otolaryngology and Pediatrics at the University of Texas Southwestern, is a co-author and site principal investigator for the study. He notes that “parents should look for daytime symptoms of attention and concentration problems, sleepiness and poor school performance...over a 3 month [timeframe in a child] who is snoring at night.” If these issues are getting worse, he recommends that “they should be evaluated by their pediatrician and considered for an ear, nose and throat evaluation.”

The study authors have some explanations as to why there was no discernible difference in executive function and attention in this group of children who had their tonsils and adenoids removed. One possibility is that cognitive testing in certain environments such as a testing center may not reflect real-world situations that could be impacted by sleep quality. In addition, there could have been other factors in the children’s lives, such as other medical conditions or learning differences that may have impacted the degree of change in test results from before to after surgery.

And while study data and clinical trials enhance our knowledge of medical conditions and their treatments, results should not be wholly used to guide care in all individuals. As Dr. Mitchell states, “Clinical trials provide us with helpful data and can direct care. However, the decision to proceed with surgery is best done on a case by case basis.”

In accurate years, there has been more awareness and understanding of how sleep quality, not just quantity, can impact a child’s ability to focus, learn and regulate behaviors. The results of this new study underscore the importance of identifying and addressing issues of sleep quality and how it may or may not impact a child’s daytime function on multiple levels.

Mon, 11 Dec 2023 07:39:00 -0600 Nina Shapiro en text/html https://www.forbes.com/sites/ninashapiro/2023/12/11/new-study-how-tonsillectomy-can-help-behavior-of-children-who-snore/
Pets can help slow dementia progress among those over age 50 who live alone, study says

A new study suggests getting that cute dog in one's more mature years might be a good idea after all. 

Researchers from the Sun Yat-sen University in Guangzhou, China, found that pet ownership can be associated with slower rates of developing dementia. 

The study, published on Tuesday in JAMA Network Open, determined that owning a pet made a difference in verbal memory and fluency among adults who lived alone.

NEW STUDY SHOWS THE EFFECT OWNING PETS HAS ON OWNERS' BRAINS

The study's author, professor Ciyong Lu, said in the study that slower rates of declining verbal memory and fluency were seen in those who lived alone — but not in those who lived with others.

"Pet ownership offset the associations between living alone and declining rates [of] verbal memory and verbal fluency," he said. 

Researchers found that owning a pet helps those with dementia.  (iStock)

The research involved more than 7,900 participants over the age of 50, with roughly 35% of them owning pets and 27% of them living alone.

In the study, Lu said that those living alone with a pet showed slower rates of developing signs of dementia.

DOG OWNER GOOD NEWS: PETTING YOUR DOG MAY LEAD TO STRONGER MEMORY AND BETTER PROBLEM SOLVING SKILLS

"These findings suggest that pet ownership may be associated with slower cognitive decline among older adults living alone," he said.

"Contrary to living alone," the authors also wrote, "pet ownership (for example, raising dogs and cats) is related to reduced loneliness, an important risk factor for dementia and cognitive decline."

A new study found that owning a pet could be beneficial for people with signs of dementia who live alone.  (iStock)

Lu said that clinical trials will be necessary in order to confirm the study's findings.

Currently, more than 55 million people worldwide have dementia — with nearly 10 million new cases each year, according to the World Health Organization (WHO). 

EATING ONE POPULAR FRUIT COULD HELP REDUCE YOUR CHANCES OF DEVELOPING DEMENTIA, STUDY FINDS

Alzheimer's disease is the most common form of dementia, which is currently the 7th leading cause of death, the WHO also notes. 

Early symptoms of dementia include forgetfulness, being confused, losing track of time, misjudging distances, feeling anxious, experiencing personality changes, engaging in inappropriate behavior and more. (iStock)

Early symptoms of dementia include forgetfulness, being confused, losing track of time, misjudging distances, feeling anxious, personality changes, inappropriate behavior and more.

CLICK HERE TO GET THE FOX NEWS APP

There is currently no cure for dementia or for someone developing signs of dementia, but the WHO suggests that staying active and continuing to stimulate the brain may help.

CLICK HERE TO SIGN UP FOR OUR LIFESTYLE NEWSLETTER

Fox News Digital reached out to Lu for further comment. 

For more Lifestyle articles, visit www.foxnews.com/lifestyle.

Tue, 26 Dec 2023 03:55:00 -0600 Fox News en text/html https://www.foxnews.com/lifestyle/pets-can-help-slow-dementia-progress-those-age-50-live-alone-study
Aspirin May Help Stop Aortic Aneurysm From Growing
  • A new study finds that aspirin may help reduce the progression of an aneurysm.
  • Currently, managing risk factors — like smoking and blood pressure — is the best way to prevent abdominal aortic aneurysm.
  • Researchers say there is a need for more medications to help control aneurysms.

Aspirin may slow abdominal aortic aneurysm (AAA) progression, a new study has found.

While aspirin didn’t appear to impact the risk of rupture, major bleeding or death, the findings, published inJAMA Network Open Tuesday, suggest that aspirin could be used to delay AAA progression in certain patients.

Currently, managing risk factors — like smoking and blood pressure — is the best way to prevent AAA and there’s a need for medications to slow the growth of these types of aneurysms.

Blood pressure lowering medications and certain antibiotics do not appear to impact progression or the risk of rupture, past evidence suggests.

Aspirin is an anti-platelet medication and preclinical studies have shown that platelet activation plays a role in the development and progression of AAA.

Additionally animal models have found that anti-platelet drugs may prevent clot formation, however, it’s been unclear if they have this same effect in humans.

Research has also explored the use of anti-platelet drugs with other types of aneurysms, including intracranial aneurysms, but the evidence has been mixed.

“This is a critical area of clinical investigation, as no medical therapy has previously been shown to be effective in [preventing] disease progression,” said Dr. Ronald Dalman, a professor of vascular surgery at Stanford Medicine. Dalman was not involved in the study.

The report included a total of 3,435 people who had at least two vascular ultrasounds conducted at the Cleveland Clinic.

The patents were followed up with for 10 years.

The researchers tracked the following outcomes: death due to any cause, major bleeding episodes, and aneurysm dissection, rupture, or repair.

Of the group, 2,150, or 63%, took aspirin by prescription.

The researchers found that the progression of the aneurysm was significantly slower among those who took aspirin.

However, aspirin use was not associated with a risk of death due to any cause, a major bleeding episode, or aneurysm dissection, rupture, or repair.

This was a retrospective study, so only correlation, not causation, can be inferred, Dalman noted.

It’s worth noting that patients taking aspirin were also more likely to be taking other medications that could potentially impact AAA progression, such as metformin and statins, Dalman added.

Still, doctors say the findings suggest aspirin might be a useful treatment option for people with AAA.

“This was the first large-scale study to specifically examine the role of aspirin in patients with AAA and is the first study that shows a correlation between a medical therapy (aspirin) and decreased growth of AAA,” said Dr. Cheng-Han Chen, an interventional cardiologist and medical director of the Structural Heart Program at MemorialCare Saddleback Medical Center in Laguna Hills, CA. Chen was not involved in the study.

Metformin, a drug that helps control blood sugar levels, is associated with slower aneurysm progression, however, it’s been difficult to find other medications that may slow AAA growth.

“Previous studies have tested many types of drug classes including beta-blockers and angiotensin-converting enzyme inhibitors, without showing any benefit,” says Chen.

The researchers suspect that, based on the findings, aspirin may help fill that gap.

According to Dalman, there are several potential mechanisms that can explain aspirin’s benefits.

For example, he says aspirin may reduce the size and accumulation of blood clots that can develop on the wall of the aneurysm as it gets bigger.

“It is possible that increased platelet activation along with increased inflammatory response within the aneurysm drives AAA growth, and that aspirin ameliorates this effect,” says Chen.

That said, because aspirin didn’t appear to prevent rupture or reduce the need for surgical repair, it’s unclear how useful the drug may be, says Dalman.

Dalman hopes the results inspire future studies to explore the effects of aspirin along with other anti-platelet therapies in AAA disease management.

“Having cross-sectional imaging studies available to evaluate the effect of aspirin therapy on thrombus accumulation and the relationship between thrombus volume and AAA diameter change, would be the next, most important questions to consider,” he said.

A new report found that aspirin may slow abdominal aortic aneurysm (AAA) progression. Scientists have struggled to find medications that can slow the growth of these types of aneurysms. Future studies will need to explore the effects of aspirin on AAA development.

Mon, 11 Dec 2023 10:00:00 -0600 en text/html https://www.healthline.com/health-news/aspirin-may-help-stop-aortic-aneurysm-from-growing
Ozempic could help curb alcohol abuse, study reveals

The latest weight loss craze could also help people control their drinking.

Semaglutide treatments such as Ozempic and Wegovy have been shown to reduce the symptoms of alcohol use disorder (AUD), according to a study published in The Journal of Clinical Psychiatry on Nov. 27.

The collaborative study from The University of Oklahoma (OU) and Oklahoma State University (OSU) found a “significant and noteworthy decrease” in the Alcohol Use Disorders Identification Test (AUDIT) scores of six patients who were receiving semaglutide treatment for weight loss.

Lead study author Dr. Jesse Richards, director of obesity medicine and assistant professor of medicine at the OU-TU School of Community Medicine, said the study was inspired by his conversation with Dr. Kyle Simmons, professor of pharmacology and physiology at the OSU Center for Health Sciences.

“I had been hearing from a significant number of patients that their alcohol intake was spontaneously decreasing while [they were] on the medication,” Richards told Fox News Digital.

As a bariatric surgery clinic employee, Richards noted that it’s standard to screen patients for alcohol use.

Studies found that there was a decrease in Alcohol Use Disorders Identification Test (AUDIT) scores for six patients receiving weight-loss treatments. AP

At the clinic, a number of patients tested positive for alcohol consumption, sometimes in concerning amounts.

Later, while on semaglutide medication, they reported reduced alcohol intake.

One of Richards’ patients — who previously drank large amounts of alcohol — shared a new inability to drink more than two cans of beer now because it “just doesn’t sound good.”

After semaglutide medication, a patient who formerly drank beer regularly began to think that alcohol just didn’t “sound good.” Getty Images

This response piqued Richards’ interest in learning more about patients’ aversion to alcohol, which directly correlated to his research.

Research has shown that this effect is “mediated through adjustments in the reward pathway in the brain,” he said.

“The GLP-1s are actually modifying dopamine, decreasing the craving and decreasing the motivation to acquire things in that compulsive intake category.”

The most surprising takeaway from the study, Richards said, was that the same significant treatment response was seen even at very low doses.

“We found that even patients on the lowest dose of semaglutide — a quarter milligram — had a quite significant and relatively … quick onset reduction in alcohol intake,” he said.

Of the six patients studied, all but one were on low doses — from a quarter to a half milligram.

“And that’s very encouraging because we know that the lower doses of these medications are tolerated much better,” said Richards.

While the results seem promising, the doctor said he does not recommend that patients use semaglutide treatments for alcohol use disorder at this time, due to supply and safety issues.

“If patients have [obesity and diabetes] indications for the medication and they also struggle with alcohol intake … having them on this treatment may potentially be beneficial,” Richards said.

Due to medication shortages and a lack of long-term data, it may not be advisable to take Ozempic to target alcoholism specifically. NurPhoto via Getty Images

“But because there has been a global medication shortage, and because we don’t have prospective trials and don’t know what the specific safety is versus the well-established safety data in obesity and diabetes, [I] would not recommend it just for patients who have AUD.”

There are three FDA-approved drugs available for alcoholic use disorder that are currently underused, the doctor noted.

Given that five million people in the U.S. are currently taking semaglutide medications, if it is proven that those drugs have a significant effect on alcohol use disorder, “by default, they are going to become the most widely used drug to Boost these symptoms — just by virtue of the fact that so many people are on them for diabetes or obesity,” Richards noted.

Trials are underway to gather more information on the weight-loss medication and its effect on alcohol intake. UCG/Universal Images Group via G

He confirmed that additional research is underway with two ongoing trials.

“Since we were able to show clinically meaningful reductions in alcohol intake and AUD symptomatology in a real-world setting, that bodes very well for these types of medications,” he said.

Looking ahead, Richard said there is a need for higher-quality evidence of the medication’s impact on AUD compared to placebo drugs or environmental factors.

People struggling with alcohol use should speak with their healthcare provider. Getty Images

Even though it’s unclear whether GLP-1 producers will market the medication to AUD patients in the future, Richards said this could become an “established medical practice once the safety and efficacy has been determined.”

For patients who struggle with AUD, Richards recommended they talk to their health care providers about available treatment.

He also alerted patients that if they experience a reduced appetite and usually consume “a bunch of calories” in alcohol, it may be necessary to look into a more balanced diet.

Avantika Waring, 9amHealth’s chief medical officer and a trained physician and endocrinologist in San Francisco, applauded the OU and OSU study findings for further supporting what clinicians “are already seeing in practice,” she told Fox News Digital.

“GLP-1 medications have a lot of effects that we are still learning about, and the ability to decrease cravings and the reward signals related to alcohol use are just some of the benefits,” she said.

“It’s an important starting point for further clinical trials,” she added.

Waring also warned that GLP-1 medications should not be used to treat AUD specifically, as they can cause side effects such as nausea and changes in appetite.

“People struggling with alcohol use disorder should consult with their physicians before starting GLP-1 medications to make sure that they can stay hydrated and safe on therapy,” she said.

Waring noted that if ongoing clinical trials find semaglutide treatments to be effective for AUD, the medical community will “have another tool to help people living with alcohol addiction and we’ll see expanded use of these already popular drugs.”

Fox News Digital reached out to Novo Nordisk for comment on the potential link between semaglutide medications and alcohol use disorder.

Sun, 10 Dec 2023 02:53:00 -0600 en-US text/html https://nypost.com/2023/12/10/lifestyle/ozempic-could-help-curb-alcohol-abuse-study-reveals/
Study: Mindfulness May Help People Stick to the DASH Diet Better
  • New research found that mindfulness helps people stick with the DASH diet.
  • The DASH diet is known to lower blood pressure and may be a good option for people with hypertension.
  • Experts recommend practicing small, mindful habits over longer periods of time to see the best results.

Mindfulness could help you stick to the DASH diet, a new study finds.

Sticking to a new eating plan can be difficult, but certain habits and disciplines may help.

New research, published last month in JAMA Network Open, found that practicing mindfulness helps people better follow the Dietary Approaches to Stop Hypertension (DASH) diet, which is known to lower blood pressure.

Not only did the people Boost self-awareness, but they stuck more accurately to the DASH healthy eating pattern, Eric B. Loucks, PhD, study author and an associate professor and director of the c at Brown University, told Health.

For the study, Loucks and his team used the Mindfulness-Based Blood Pressure Reduction (MB-BP) program, which has been previously confirmed as effective at reducing systolic blood pressure.

“This research has direct implications for bringing awareness into people’s lives regarding modifiable determinants of hypertension,” Maryanna D. Klatt, PhD, director of the Center for Integrative Medicine and a mindfulness educator at The Ohio State University College of Medicine, told Health.

Loucks’ MB-BP program uses a combination of emotional regulation, yoga, self-awareness, and attention control.

It centers on teaching those tools to lower blood pressure, specifically. It’s based on Mindfulness-Based Stress Reduction (MBSR), a proven method of using mindfulness to achieve goals.

Here’s how mindfulness may impact the success of the DASH diet, as well as tips for being more mindful in your day-to-day routine.

Getty Images / LumiNola

Loucks’ study focused on mindfulness education and practice to follow the DASH diet and lower blood pressure.

99 participants attended an orientation, eight 2.5-hour group sessions a week, and went to a one-day retreat—10 sessions of training total. Each participant received individualized education about hypertension, behavior change support, and learned about mindful eating for hypertension.

People in the program were encouraged to practice mindfulness techniques at home for 45 minutes a day, six days a week.  

The control group, on the other hand, only received educational materials on how to control blood pressure. 

Everyone in the trial received and was trained on how to use a home blood-pressure monitor, and got information on local primary care doctors.  

All of the participants had elevated blood pressure. At the beginning of the trial, none of them meditated more than once a week.

To see how well the MB-BP program worked, researchers used two scores: a Multidimensional Assessment of Interoceptive Awareness (MAIA) questionnaire and a DASH adherence score.

The MAIA uses a 0–5 score and is intended to assess how in tune people are with their body’s sensations and cues. The DASH adherence score ranges from 0–11 and gauges how well people stuck to the diet.

Six months into the study, participants in the mindfulness training program saw a 0.71-point increase in their MAIA score—that was 0.54 points higher than the median score of the control group. Similarly, people in the program increased their median DASH adherence score by 0.34, while people in the control group saw a 0.04-point decrease.

In the future, Loucks wants to assess if the MB-BP program still works as well with fewer sessions or a shorter program length. He also wants to see how well MB-BP would work in real-world settings, and how insurers may be able to cover it.

Many people eat in response to environmental and emotional triggers, rather than using cues of hunger and satiety to guide their eating, Michelle May, MD, a retired doctor and mindful eating educator from Phoenix, AZ, told Health after reviewing the research.

Environmental triggers include seeing commercials for food or situations you associate with eating—like a movie theater, baseball game, or the holidays.

Emotional triggers include stress, boredom, or loneliness—and even pleasant emotions like celebrations, said May.

“Mindfulness helps you change habitual, mindless, reactive behaviors because being in the present moment allows you to consciously choose your response,” she said. 

According to Loucks, three areas make mindfulness effective at impacting eating habits:

  1. Self-awareness: Noticing hunger and fullness, how different foods make you feel, and being aware of eating behaviors and habits
  2. Attention control: Being present when you eat, making conscious choices for healthy eating patterns, making choices against possibly unconscious unhealthy eating patterns, and making intentional choices when choosing food at restaurants and while grocery shopping
  3. Emotion regulation: Lowering your reactivity to food cravings, practicing self-kindness and compassion for your body and mind, and reducing psychological distress that can keep you from adhering to your desired eating patterns

Mindful eating can look different for everyone.

When it comes to sticking with the DASH diet, you may focus more on making choices about what goes into your food (while someone using mindful eating to reduce portion sizes may focus their approach on eating less).

Low sodium and low saturated fat are two hallmarks of the DASH diet. If you want to be more intentional about reducing your intake, you might use a mindfulness tool that helps you avoid or reduce the amount of salt you put in a meal. Or you might practice mindfulness when shopping for ingredients low in saturated fat.

In addition to learning mindfulness tools, it matters how often or how long you practice them, too.

According to Loucks, you’ll probably get better results the longer you practice but you’ve got to find the right amount of time that works for you.

“It comes down to awareness, compassion, and willingness to adopt the change you desire,” added Klatt.

Mindfulness is effective if you incorporate it into your daily life—even in small, but significant ways.

Klatt concluded: “These small ways can add up to very big changes in the way we approach our days.”

Thu, 07 Dec 2023 10:00:00 -0600 en text/html https://www.health.com/mindfulness-for-healthy-eating-8391138
Ozempic and Wegovy weight loss drugs could help reduce alcohol use disorder symptoms, study suggests

The latest weight loss craze could also help people control their drinking.

Semaglutide treatments such as Ozempic and Wegovy have been shown to reduce the symptoms of alcohol use disorder (AUD), according to a study published in The Journal of Clinical Psychiatry on Nov. 27.

The collaborative study from The University of Oklahoma (OU) and Oklahoma State University (OSU) found a "significant and noteworthy decrease" in the Alcohol Use Disorders Identification Test (AUDIT) scores of six patients who were receiving semaglutide treatment for weight loss.

OZEMPIC DIABETES AND WEIGHT LOSS MEDICATION UNDER INVESTIGATION AFTER A FEW REPORTS OF SUICIDAL THOUGHTS

Lead study author Dr. Jesse Richards, director of obesity medicine and assistant professor of medicine at the OU-TU School of Community Medicine, said the study was inspired by his conversation with Dr. Kyle Simmons, professor of pharmacology and physiology at the OSU Center for Health Sciences.

"I had been hearing from a significant number of patients that their alcohol intake was spontaneously decreasing while [they were] on the medication," Richards told Fox News Digital.

Semaglutide treatments such as Ozempic and Wegovy have been shown to reduce symptoms of alcohol use disorder, according to a new study published in The Journal of Clinical Psychiatry. (iStock; SEBASTIEN BOZON/AFP via Getty Images)

As a bariatric surgery clinic employee, Richards noted that it’s standard to screen patients for alcohol use.

OZEMPIC-WEGOVY PILL MAY BE ON THE WAY: TRIAL SHOWS PROMISING RESULTS FOR NEW WEIGHT LOSS TABLET

At the clinic, a number of patients tested positive for alcohol consumption, sometimes in concerning amounts.

Later, while on semaglutide medication, they reported reduced alcohol intake.

Dr. Jesse Richards is director of obesity medicine at OU Health at the Hardesty Center for Clinical Research and Neuroscience in Tulsa, Oklahoma. "I had been hearing from a significant number of patients that their alcohol intake was spontaneously decreasing while on the medication," he told Fox News Digital.  (OSU Center for Health Sciences)

One of Richards’ patients — who previously drank large amounts of alcohol — shared a new inability to drink more than two cans of beer now because it "just doesn’t sound good."

This response piqued Richards' interest in learning more about patients' aversion to alcohol, which directly correlated to his research.

 Only about 2% of people with alcohol use disorder are on an approved treatment.

Research has shown that this effect is "mediated through adjustments in the reward pathway in the brain," he said.

"The GLP-1s are actually modifying dopamine, decreasing the craving and decreasing the motivation to acquire things in that compulsive intake category."

"Reducing liquid sugar and liquid caloric intake is strongly associated with effective weight loss," an expert told Fox News Digital. (iStock)

The most surprising takeaway from the study, Richards said, was that the same significant treatment response was seen even at very low doses.

"We found that even patients on the lowest dose of semaglutide — a quarter milligram — had a quite significant and relatively … quick onset reduction in alcohol intake," he said.

Of the six patients studied, all but one were on low doses — from a quarter to a half milligram.

OZEMPIC, WEGOVY MAY BE LINKED TO STOMACH PARALYSIS AND OTHER DIGESTIVE ISSUES IN LARGE-SCALE STUDY

"And that's very encouraging because we know that the lower doses of these medications are tolerated much better," said Richards.

While the results seem promising, the doctor said he does not recommend that patients use semaglutide treatments for alcohol use disorder at this time, due to supply and safety issues.

Wegovy is an injectable prescription weight loss medicine that has helped people address obesity. (Michael Siluk/UCG/Universal Images Group via Getty Images)

"If patients have [obesity and diabetes] indications for the medication and they also struggle with alcohol intake … having them on this treatment may potentially be beneficial," Richards said.

"But because there has been a global medication shortage, and because we don't have prospective trials and don't know what the specific safety is versus the well-established safety data in obesity and diabetes, [I] would not recommend it just for patients who have AUD."

OZEMPIC, WEGOVY AND PREGNANCY RISK: WHAT YOU NEED TO KNOW ABOUT THE ISSUE

There are three FDA-approved drugs available for alcoholic use disorder that are currently underused, the doctor noted.

"Unfortunately, at this point, only about 2% of people with AUD are on an approved treatment," he said.

GLP-1 treatments do not have a warning against consuming alcohol while taking the drugs, an expert pointed out. (iStock)

Given that five million people in the U.S. are currently taking semaglutide medications, if it is proven that those drugs have a significant effect on alcohol use disorder, "by default, they are going to become the most widely used drug to Boost these symptoms — just by virtue of the fact that so many people are on them for diabetes or obesity," Richards noted.

OZEMPIC, WEGOVY AND ALL THOSE CRAZY, VIVID DREAMS: IS THERE A CONNECTION?

He confirmed that additional research is underway with two ongoing trials.

"Since we were able to show clinically meaningful reductions in alcohol intake and AUD symptomatology in a real-world setting, that bodes very well for these types of medications," he said.

Looking ahead, Richard said there is a need for higher-quality evidence of the medication's impact on AUD compared to placebo drugs or environmental factors.

Health care providers wrote more than nine million prescriptions for Ozempic and similar drugs in the last quarter of 2022, data shows. (SEBASTIEN BOZON/AFP via Getty Images)

Even though it’s unclear whether GLP-1 producers will market the medication to AUD patients in the future, Richards said this could become an "established medical practice once the safety and efficacy has been determined."

For patients who struggle with AUD, Richards recommended they talk to their health care providers about available treatment.

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He also alerted patients that if they experience a reduced appetite and usually consume "a bunch of calories" in alcohol, it may be necessary to look into a more balanced diet.

Avantika Waring, 9amHealth's chief medical officer and a trained physician and endocrinologist in San Francisco, applauded the OU and OSU study findings for further supporting what clinicians "are already seeing in practice," she told Fox News Digital.

"People struggling with alcohol use disorder should consult with their physicians before starting GLP-1 medications."

"GLP-1 medications have a lot of effects that we are still learning about, and the ability to decrease cravings and the reward signals related to alcohol use are just some of the benefits," she said.

"It’s an important starting point for further clinical trials," she added.

Waring also warned that GLP-1 medications should not be used to treat AUD specifically, as they can cause side effects such as nausea and changes in appetite.

Patients' aversion to alcohol is part of balancing the "side effects with the benefit" of the medication, said the lead study author. (iStock)

"People struggling with alcohol use disorder should consult with their physicians before starting GLP-1 medications to make sure that they can stay hydrated and safe on therapy," she said.

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Waring noted that if ongoing clinical trials find semaglutide treatments to be effective for AUD, the medical community will "have another tool to help people living with alcohol addiction and we’ll see expanded use of these already popular drugs."

Fox News Digital reached out to Novo Nordisk for comment on the potential link between semaglutide medications and alcohol use disorder.

For more Health articles, visit www.foxnews.com/health.

Sat, 09 Dec 2023 20:30:00 -0600 Fox News en text/html https://www.foxnews.com/health/ozempic-wegovy-weight-loss-drugs-reduce-alcohol-use-disorder-symptoms-study
The Deals: WMG to Help Study ‘Music as Medicine’; Secretly to Distribute for Madlib, David Gray & More

Warner Music Group has partnered with British health tech start-up MediMusic to trial “music as medicine” to help relieve pain, anxiety and stress. MediMusic will conduct research testing in several closed randomized controlled trials in both the United States and the United Kingdom that will deliver playlists from the Warner Music catalog to patients and trial groups to observe how they respond to the music in real-time.

“MediMusic’s proprietary algorithms extract the relevant features from the digital DNA of a piece of music, resulting in a fingerprint for healthcare use,” according to a press release, with the help of artificial intelligence, machine learning and patient data. The company then automatically creates personalized 20-minute playlists and plays the music through a streaming device called the MediBeat and a pair of headphones. Patients wear a heart rate monitor on their wrists to monitor the physiological effect of a piece of music.

More from Billboard

The release states that initial trials conducted by MediMusic and the UK National Health Service using the MediMusic technology reduced the heart rate of anxious dementia patients by 25%.


Secretly Distribution announced new global multi-year deals with Danger Mouse‘s 30th Century Records, the catalog of singer-songwriter David Gray and Madlib‘s Madlib Invazion. Secretly will support all of 30th Century Records’ new music and back catalog, including vinyl reissues. For the Gray catalog, the company will work with Bella Figura Music to provide the catalog with global digital support and vinyl reissues. And for Madlib Invazion, Secretly will handle distribution for Madlib and the rest of the label, including new music from Madlib expected next year.

Additionally, Secretly announced multi-year contract renewals with three longtime label partners: Captured Tracks, Rhymesayers Entertainment and Run for Cover.


SoundCloud announced partnerships with dance label Helix Records and hip-hop label Payday Records to offer expanded global artist services for emerging electronic and hip-hop artists identified by SoundCloud for a potential signing with one of the labels.


ASM Global and Voltus, a distributed energy resource platform and virtual power plant operator, struck a partnership through which ASM Global-managed venues will be paid for energy reduction efforts across all venues located in wholesale and regulated power markets in the United States. Earlier this year, the ASM Global Acts Foundation announced a plan to convert the company’s venue portfolio into the world’s most sustainable, which includes reducing energy consumption by 25% by 2030 from this year’s baseline and becoming carbon neutral by 2050.


Colorado Springs, Colo.-based live entertainment company Notes Live entered into a non-binding letter of intent for a business combination transaction with wine producer Fresh Vine Wine, a company listed on the NYSE American stock exchange. The two parties expect to negotiate and enter into a definitive agreement before the end of January; Notes Live is planning to seek shareholder approval for the transaction at a meeting scheduled for Jan. 31.

The final closing is expected in the second quarter of 2024, subject to closing conditions including approvals by NYSE American of the continued listing of the combined company’s common stock after the closing. The combined company’s common stock would trade on the NYSE American under the ticket “VENU” following the closing.

Notes Live currently operates two entertainment campsites in Colorado Springs and Gainesville, Ga. and is also developing luxury amphitheaters in Colorado Springs; Broken Arrow and Oklahoma City, Okla.; and northern Texas. According to a press release, “The parties expect that the owners of Notes Live would own a substantial majority of the issued and outstanding shares of Fresh Vine common stock on a post-transaction basis, which may be in excess of 90%.”


The Feldman Agency is teaming with Tennis Canada to launch The Bowl at Sobeys Stadium, a new open-air concert venue in Toronto. Located on the York University campus, the Bowl will accommodate up to 9,000 guests and feature private lounges and an onsite restaurant.


Lucas Thomashow, former senior vp at Avex, announced SANA, a new label that will be a joint venture with recently launched artist and label services company Santa Anna (led by Todd Moscowitz and Lee L’Heureux), Sony Music and independent label LISTEN TO THE KIDS (founded by Conor Ambrose). SANA’s partnership with Santa Anna will encompass distribution, marketing and promotion, while the A&R and marketing teams at LISTEN TO THE KIDS (which partnered with Santa Anna in January 2023) will work with SANA on the strategy and development of the label. SANA will be based in LISTEN TO THE KIDS’ studio and offices in L.A.


Production company Jesse Collins Entertainment has signed with CAA for representation. The company, which boasts three divisions — specials, unscripted and scripted — is next slated to produce the 75th annual Emmy Awards. The company’s credits include the American Music Awards, BET Awards, Becoming a Popstar, Cardi Tries, American Soul and The New Edition Story. Founder/CEO Jesse Collins and president Dionne Harmon executive produce all Jesse Collins Entertainment programming; the company has a multi-year, non-exclusive overall deal with Paramount Global.


Lyric licensing and data solutions company LyricFind and music metadata leader Music Story extended and expanded their multi-year relationship. The broader partnership allows Music Story to help further LyricFind’s commercial reach by selling the company’s services to customers in the United States and globally. Prospective customers can also tap Music Story’s U.S. and international metadata services.

“By making Music Story an extension of LyricFind’s services, we’re taking a major step forward in unlocking the power of metadata to help more people discover and enjoy the music they love with lyrics while ensuring that songwriters and copyright holders are fairly compensated for their incredible work,” said LyricFind founder/CEO Darryl Ballantyne in a statement.


B2B streaming media service Tuned Global partnered with the new “artist-centric” streaming platform Sona to help launch Sona’s music service and marketplace, sona.stream. Tuned Global will provide content delivery, tools and reporting services for Sona under the deal, including its content delivery and APIs that will allow fans to create playlists and launch radio stations based on their favorite artists (beginning in 2024).

Co-founded by artist/producer TOKiMONSTA and Laura Jaramillo, Sona allows fans to stream music for free without subscriptions or ads but also to buy SONAs, or digital twins of specific songs that share future streaming rewards with their owners. Artists can choose which songs to auction as SONAs, while fans can purchase songs as SONAs to earn 70% of that song’s future streaming rewards on the Sona platform.


Beats marketplace BeatStars has partnered with software developer Resonant Cavity, creators of the popular mobile studio and vocal effects app Voloco, to integrate with Voloco beginning in January. “Our collaboration with BeatStars will bring the best beat catalog into the most powerful mobile recording studio,” said Patrick Flanagan, CEO/founder of Resonant Cavity, in a statement. “As artists experience studio-quality vocals from Voloco over top-tier beats from BeatStars producers, they’re going to be inspired to create something exceptional.”

Best of Billboard

Thu, 14 Dec 2023 04:35:00 -0600 en-US text/html https://www.yahoo.com/entertainment/deals-wmg-help-study-music-183538573.html




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