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Killexams : Medical Specialist study - BingNews https://killexams.com/pass4sure/exam-detail/FNS Search results Killexams : Medical Specialist study - BingNews https://killexams.com/pass4sure/exam-detail/FNS https://killexams.com/exam_list/Medical Killexams : Researchers at UArizona Health Sciences awarded $7.3M to Study Long COVID KOLD © Provided by Tucson (Sierra Vista) KOLD KOLD

TUCSON, Ariz. (KOLD News 13) - Millions of people around the world are struggling with Long COVID. Thanks to a $7.3 million grant from the CDC, UArizona Health Sciences will now explore potential solutions for improving the health and well-being of people affected with long COVID across the state.

Researchers are trying to determine what long COVID looks like and how many people across the state are experiencing those symptoms. So far, they’re working with 8,500 people, with a goal of following atleast 1,000 people over the next five years.

“Some people will start having symptoms when they get sick and just never really get better. Other people will have a fairly mild acute infection and recover and then start to have all these other issues they weren’t anticipating,” said Kristen Pogreba Brown, Associate Professor in Epidemiology and Biostatistics at the College of Public Health.

Because there are so many unanswered questions surrounding long haul COVID, researchers are hoping not only to figure out what the long term effects are, but how it impacts different age groups and populations.

“We are capitalizing on the existence of the CoVHORT to try to find 1,000 people who are struggling with long COVID and see how it happens over time. How quickly or shortly it evolves. If additional symptoms pop up when they’re suffering,” said Jennifer Andrews, Associate Professor of Pediatrics at the College of Medicine Tucson.

And those symptoms look different for everyone.

“Brain fog is one. We’re seeing a lot of neurological changes. Everything from neuropathy to weakness in muscles and other things. Pulmonary is one we’re seeing a lot of, so people who had a lot of lung issues when they got sick are continuing to have those issues. A lot of shortness of breath,” Pogreba Brown said.

We’re told most of the patients struggle with more than one symptom. Leah Vaughan has been struggling for nearly a year with brain fog, trouble sleeping and heart problems.

“I could be driving into work and my heart would start beating and it would go up to about 130 beats per minute just sitting in the car driving. Just walking from the car into work I was out of breath. My hear rate was up as well then and it got to the point where I knew there was something going on,” Vaughan said.

Getting in to see a specialist was not an easy task, and she says she’s now left with more questions than answers.

“The nerves and wondering how and what. Was it the COVID was it the vaccine, what was it and no one can tell you what it was,” Vaughan said.

Pogreba Brown said the same thing is happening to a lot of people.

“People are trying to go to one specialist and then another and then another and that’s extremely frustrating for people and not really efficient in our medical system either so we’re hoping through this study more broadly and partnering with some of our clinical partners to start pulling all of these pieces together to see if there are more syndrome based diagnosis to see what symptoms kind of cluster together,” Pogreba Brown said.

If you’ve had COVID-19 and you experienced symptoms for more than 30-days, you by definition have long COVID.

Other long haulers have a mild case of COVID then experienced new conditions weeks or months later.

If you fall into either category, the researchers want your help.

You can sign up for the study online.

Thu, 08 Dec 2022 19:21:00 -0600 en-US text/html https://www.msn.com/en-us/health/medical/researchers-at-uarizona-health-sciences-awarded-73m-to-study-long-covid/ar-AA154Mhs
Killexams : Dementia risk may increase if you’re eating these foods, study says

(CNN) — We all eat them — ultraprocessed foods such as frozen pizza and ready-to-eat meals make our busy lives much easier. Besides, they are just darn tasty — who isn’t susceptible to hot dogs, sausages, burgers, french fries, sodas, cookies, cakes, candy, doughnuts and ice cream, to name just a few?

If more than 20% of your daily calorie intake is ultraprocessed foods, however, you may be raising your risk for cognitive decline, a new study found.

That amount would equal about 400 calories a day in a 2,000-calories-a-day diet. For comparison, a small order of fries and regular cheeseburger from McDonald’s contains a total of 530 calories.

The part of the brain involved in executive functioning — the ability to process information and make decisions — is especially hard hit, according to the study published Monday in JAMA Neurology.

Men and women in the study who ate the most ultraprocessed foods had a 25% faster rate of executive function decline and a 28% faster rate of overall cognitive impairment compared with those who ate the least amount of overly processed food.

“While this is a study of association, not designed to prove cause and effect, there are a number or elements to fortify the proposition that some acceleration in cognitive decay may be attributed to ultraprocessed foods,” said Dr. David Katz, a specialist in preventive and lifestyle medicine and nutrition, who was not involved in the study.

“The trial size is substantial, and the follow-up extensive. While short of proof, this is robust enough that we should conclude ultraprocessed foods are probably bad for our brains.”

There was an interesting twist, however. If the quality of the overall diet was high — meaning the person also ate a lot of unprocessed, whole fruits and veggies, whole grains and healthy sources of protein — the association between ultraprocessed foods and cognitive decline disappeared, Katz said.

“Ultraprocessed foods drag diet quality down, and thus their concentration in the diet is an indicator of poor diet quality in most cases,” Katz said. “Atypical as it seems, apparently some of the participants managed it. And when diet quality was high, the observed association between ultraprocessed foods and brain function abated.”

A lot of ultraprocessed foods

The study followed over 10,000 Brazilians for up to 10 years. Just over half of the study participants were women, White or college educated, while the average age was 51.

Cognitive testing, which included immediate and delayed word recall, word recognition and verbal fluency, was performed at the beginning and end of the study, and participants were asked about their diet.

“In Brazil, ultraprocessed foods make up 25% to 30% of total calorie intake. We have McDonald’s, Burger King, and we eat a lot of chocolate and white bread. It’s not very different, unfortunately, from many other Western countries,” coauthor Dr. Claudia Suemoto, an assistant professor in the division of geriatrics at the University of São Paulo Medical School, told CNN when the study abstract was released in August.

“Fifty-eight percent of the calories consumed by United States citizens, 56.8% of the calories consumed by British citizens, and 48% of the calories consumed by Canadians come from ultraprocessed foods,” Suemoto said.

Ultraprocessed foods are defined as “industrial formulations of food substances (oils, fats, sugars, starch, and protein isolates) that contain little or no whole foods and typically include flavorings, colorings, emulsifiers, and other cosmetic additives,” according to the study.

Those in the study who ate the most ultraprocessed foods were “more likely to be younger, women, White, had higher education and income, and were more likely to have never smoked, and less likely to be current alcohol consumers,” the study found.

It’s not just the brain

In addition to the impact on cognition, ultraprocessed foods are already known to raise the risk of obesity, heart and circulation problems, diabetes, cancer and a shorter life span.

“Ultraprocessed foods in general are bad for every part of us,” said Katz, president and founder of the nonprofit True Health Initiative, a global coalition of experts dedicated to evidence-based lifestyle medicine.

Ultaprocessed foods are usually high in sugar, salt and fat, all of which promote inflammation throughout the body, which is “perhaps the most major threat to healthy aging in the body and brain,” said Dr. Rudy Tanzi, professor of neurology at Harvard Medical School and director of the genetics and aging research unit at Massachusetts General Hospital in Boston. He was not involved in the study.

“Meanwhile, since they are convenient as a quick meal, they also replace eating food that is high in plant fiber that is important for maintaining the health and balance of the trillions of bacteria in your gut microbiome,” Tanzi added, “which is particularly important for brain health and reducing risk of age-related brain diseases like Alzheimer’s disease.”

What to do

How can you keep this from happening to you? If you include ultraprocessed foods in your diet, try to counter these by also eating high-quality, whole foods such as fruits, vegetables and whole grains.

“The conclusion suggested here is that ultraprocessed foods are, indeed, an important ‘ingredient,’ but the exposure that should be the focus of public health efforts is overall diet quality,” Katz said.

One easy way to ensure diet quality is to cook and prepare your food from scratch, Suemoto said.

“We say we don’t have time, but it really doesn’t take that much time,” Suemoto said.

“And it’s worth it because you’re going to protect your heart and guard your brain from dementia or Alzheimer’s disease. That’s the take-home message: Stop buying things that are superprocessed.”

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Fri, 09 Dec 2022 02:50:00 -0600 text/html https://www.eastidahonews.com/2022/12/dementia-risk-may-increase-if-youre-eating-these-foods-study-says/
Killexams : Buying Testosterone on the Internet Comes With Dangers: Study

THURSDAY, Dec. 8, 2022 (HealthDay News) -- With more American men turning to testosterone therapy as a way to boost energy levels, build muscle and tackle erectile dysfunction, it’s no wonder that web-based merchants have stepped into the breach, seeking to grab market share away from doctors and pharmacies.

But are online testosterone purchases safe? No, a new investigation warns.

The conclusion follows an anonymous testing of seven U.S.-based online entities that sell testosterone therapy to consumers across the country.

The upshot: The vast majority of online portals are perfectly willing to sell the hormone to patients who are not, in fact, testosterone-deficient. Most also fail to inquire about potentially problematic underlying conditions and neglect to caution patients about the possible risks involved, including infertility.

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“We found that most of these platforms offer treatment to men who are not considered appropriate candidates according to existing medical guidelines, and many platforms were not offering appropriate counseling regarding the risks of treatment,” said study author Dr. Joshua Halpern. He is an andrology and infertility specialist and assistant professor with Northwestern University’s Feinberg School of Medicine, in Chicago.

This is a potentially big and growing concern, the study team pointed out, given that between 2017 and 2019 there was a 1500% jump in the number of visits to direct-to-consumer online portals that claim to treat erectile dysfunction.

That said, “testosterone therapy is a well-established medical treatment for men with the condition of testosterone deficiency,” Halpern acknowledged .

Testosterone deficiency “is the combination of having low testosterone levels in the blood and having symptoms that are classically associated with low testosterone, [such as] low energy and low libido," he explained.

“Men with these symptoms seeking testosterone treatment are often trying to Excellerate their quality of life,” Halpern noted, “although some men may pursue testosterone therapy for other reasons, [including] building muscle mass.”

When prescribed to those who need it, taken as instructed and monitored appropriately, it “is generally considered safe,” he said.

Still, Halpern and his colleagues stressed that per the U.S. Drug Enforcement Administration, testosterone is deemed a controlled substance. That means that — alongside similar drugs, like anabolic steroids and the anesthetic party drug ketamine — there is a low-to-moderate risk for becoming addicted.

For that reason, Halpern said, “testosterone is typically prescribed through a local pharmacy by a health care provider, such as a primary care provider, urologist or endocrinologist.”

Even when administered appropriately and under ideal medical conditions, testosterone therapy is not without risks. Those, said Halpern, can include a thickening of the blood and infertility. It can also trigger a rare but serious rise in red blood cell counts, which can lead to blood clots and bleeding and/or raise the risk for heart attacks or stroke.

Given such concerns, Halpern and his associates wondered if approved prescribing guidelines and risk disclosures are a routine part of the online purchasing process.

Apparently not, as became evident after the team set up a “secret shopper” online profile to surf the web-based testosterone therapy options.

Fashioned as a 34-year-old man struggling with low energy and low libido — both of which typify low-testosterone levels — the “dummy” profile made clear that the patient in question was interested in trying testosterone while also remaining fertile down the road.

The profile was submitted to seven U.S. online portals that sell testosterone. Intake procedures variously involved providing lab testing results and engaging in telemedicine consults conducted by nurse practitioners, physician assistants or individuals with no medical license of any kind.

The end result: Nearly 86% of the sites offered to sell testosterone even though the dummy profile clearly noted testosterone levels that fell within the normal range. Six of the seven portals had no testosterone level threshold for providing treatment.

Only one of the portals asked about the patient’s specific heart health history or personal interest in future fertility, while only half raised potential fertility concerns. More than 83% of the time, blood thickness concerns were never mentioned, the investigators found.

“Testosterone therapy has many benefits, but it also has risks and is not appropriate for everyone,” Halpern stressed. “While online direct-to-consumer platforms offer great promise in expanding access to care for men with low testosterone, there are some drawbacks. Men should start by talking with their local health care provider before considering testosterone treatment.”

The findings were published as a research letter in the December issue of JAMA Internal Medicine.

Dr. Pieter Cohen is a general internist with Cambridge Health Alliance and an associate professor at Harvard Medical School in Boston.

Though not part of the study team, his takeaway is that the new investigation “elegantly highlights many of the pitfalls of obtaining testosterone from an online provider, even after completing blood tests.”

Cohen noted that “the patients were not properly screened, the testosterone prescription was not appropriate and, in addition to testosterone, patients were encouraged to use a host of other questionable and potentially dangerous drugs.”

Beyond that, he added that in many cases the symptoms people are quick to attribute to low testosterone are really just a function of normal aging or other illnesses. “But that hasn't stopped the marketers of testosterone to try to start everyone they can on the drug,” Cohen said.

There's more on the pros and cons of testosterone therapy at the Mayo Clinic.

SOURCES: Joshua Halpern, MD, MS, andrology and infertility specialist, and assistant professor, Feinberg School of Medicine, Northwestern University, Chicago; Pieter Cohen, MD, general internist, Cambridge Health Alliance, and associate professor, Harvard Medical School, Boston; JAMA Internal Medicine, December 2022

Thu, 08 Dec 2022 01:47:00 -0600 en text/html https://omaha.com/lifestyles/health-med-fit/buying-testosterone-on-the-internet-comes-with-dangers-study/article_8a1487d6-eb7a-55ab-8040-f528d0559b8e.html
Killexams : Canadians have never waited this long for medical treatment, study finds

The annual Fraser Institute study this year reports a median wait time of 27.4 weeks for Canadians to get treatment after a family doctor referral

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OTTAWA — Canadians are waiting longer than ever to see a doctor, says the latest annual study on medical wait times from the Fraser Institute.

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The think-tank reports a median wait time of 27.4 weeks for Canadians to get treatment, longer than the 25.6 weeks reported in 2021 and significantly longer than 9.3 weeks the institute recorded in its first wait time survey in 1993.

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The wait time includes the time period between when a patient is referred by their family doctor to a specialist, the consultation with that specialist and when they are ultimately given treatment or surgery.

This year’s survey took in responses from 850 physicians across the country. The institute said COVID-19 backlogs were part of the problem, but contended this was just more evidence of a broken health-care system.

“Excessively long wait times remain a defining characteristic of Canada’s health-care system,” said Mackenzie Moir, Fraser Institute policy analyst and co-author of the report. “And they aren’t simply minor inconveniences, they can result in increased suffering for patients, lost productivity at work, a decreased quality of life, and in the worst cases, disability or death.”

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Physicians in the survey also reported to the institute that patients were waiting an average of six weeks longer than was clinically acceptable.

The survey broke down the wait times based on medical specialities as well, with the shortest wait there for radiation treatments to treat cancer, which took on average 3.9 weeks. The longest wait time was for neurosurgery, which took 58.9 weeks, but there were also long waits for plastic surgery, which took 58.1 weeks and orthopedic surgery where patients waited on average 48.4 weeks.

The survey found that wait times to be treated were longest in Prince Edward Island at 64.7 weeks, and shortest in Ontario where they came in at 20.3 weeks. The survey was sent to physicians in the first part of the year. Since then hospitals across the country have come under increasing pressure due to outbreaks of influenza, COVID-19 and respiratory syncytial virus.

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Health Minister Jean Yves Duclos said he knows health workers are under more stress than ever.

“Obviously, the additional load that COVID-19 has brought on them with lots of backlogs and surgeries and diagnostics. So yes, it’s a very serious and severe situation now for workers and patients across Canada,” he said.

Provinces have been calling on the federal government to deliver a substantial increase, up to $28 billion, in the annual Canada Health Transfer to increase funding for hospitals, doctors and nurses in a bid to deal with staff shortages. The Liberals have indicated a willingness to increase transfers, but want the money to come with certain strings, including better data sharing and a strategy for expanding the health-care workforce.

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Duclos met with provincial health ministers last month, but the talks fell apart, ending in acrimony.

He said Thursday that while those talks didn’t produce a result, he is still talking to his provincial counterparts regularly about ways to Excellerate the system.

“I’m engaged with them almost every week and my officials talk almost every day,” he said.

Duclos pointed to recent announcements pledging to allow more foreign-trained workers to get accredited in Canada and other steps the government has taken to Excellerate the system.

He said the federal government has put a lot of money on the table as well, citing inflationary increases to the Canada Health Transfer, and money for targeted initiatives across the country.

He said money can’t be the only solution to the problem.

“The increase in the Canada Health Transfer of five per cent a few months ago, with an additional 10 per cent in March 2023, long term care, home care, mental health care additional dollars for that too, but we need to agree now on results.”

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Wed, 07 Dec 2022 21:22:00 -0600 en-CA text/html https://montrealgazette.com/news/canada/fraser-institute-wait-times-medical
Killexams : AI in Medical Diagnostics Market is Expected to Reach $9.38 Billion, at a CAGR of 36.2% from 2022 to 2029 Killexams : AI in Medical Diagnostics Market is Expected to Reach $9.38 Billion, at a CAGR of 36.2% from 2022 to 2029 | Medgadget Killexams : AI in Medical Diagnostics Market is Expected to Reach $9.38 Billion, at a CAGR of 36.2% from 2022 to 2029 |

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Wed, 07 Dec 2022 22:53:00 -0600 en-US text/html https://www.medgadget.com/2022/12/ai-in-medical-diagnostics-market-is-expected-to-reach-9-38-billion-at-a-cagr-of-36-2-from-2022-to-2029.html
Killexams : Study reports high rates of complications, rehospitalizations among patients undergoing abdominal ostomy surgery

Patients undergoing abdominal surgery for ostomy placement have high rates of hospital readmissions and emergency department visits – often involving ostomy-related complications, reports a study in the November/December issue of the Journal of Wound, Ostomy and Continence Nursing, the official journal of the Wound, Ostomy and Continence Nurses (WOCN®) Society. The Journal of WOCN® is published in the Lippincott portfolio by Wolters Kluwer.

"Our analysis of real-world, nationwide data shows the urgent need for efforts to Excellerate the outcomes for patients undergoing abdominal stoma surgery, including patient-centered care and greater access to the services of wound, ostomy and continence [WOC] nurses or ostomy nurse specialists," comments lead author Laura L. Schott, PhD, of PINC AI™ Applied Sciences (PAS), a division of PINC AI™, the technology and services platform of Premier Inc.

Forty-two percent hospital readmission rate within 120 days after ostomy surgery

The researchers analyzed data on nearly 28,000 patients undergoing abdominal ostomy surgery in 2017-18, drawn from a large US hospital database. The study included approximately 15,500 patients undergoing creation of a colostomy, 10,000 undergoing construction of an ileostomy and 1,900 undergoing urostomy placement.

Colostomies and ileostomies are openings created in the abdominal wall to allow passage of stool from the large and small intestines, respectively. Urostomies are created to allow passage of urine from the bladder. Among the study patients, the most common reasons for colostomy or ileostomy were colorectal cancer, diverticulitis, and sepsis. Bladder cancer was the main reason for urostomy.

Patient characteristics varied among groups: about 71% of colostomy patients and 49% of ileostomy patients underwent emergency surgery, compared to 10% of urostomy patients. Patients stayed in the hospital for a median of seven days after their ostomy surgery. Patients undergoing colostomy or ileostomy spent more days in the hospital, potentially reflecting their higher rates of emergency and traditional open abdominal surgery.

The data showed high rates of healthcare use in the weeks and months after stoma surgery. Within 120 days after initial hospitalization, 42% of patients were readmitted to the hospital at least once. Patients undergoing ileostomy frequently had repeat hospitalizations: 52%, compared to 36% in the colostomy group and 35% in the urostomy group. Ostomy complications were the reason for rehospitalization in about 62% of patients.

Patient education and WOC nurse specialists could play key roles in improving outcomes after ostomy surgery

About 21% of patients had ED visits within 120 days after initial hospitalization – more common for colostomy or ileostomy patients, compared to urostomy patients. About 40% of ED visits were due to ostomy-related complications.

The findings are largely consistent with previous studies showing that patients undergoing ostomy surgery are acutely ill, require several days in the hospital, and have high rates of rehospitalization, subsequent ED visits, and complications requiring follow-up care. "To address these issues, clinicians and hospital management should ensure patients receive the services of a WOC or ostomy nurse specialist, preoperative stoma marking, and post-discharge support programs that promote self-management skills and adjustment to life with an ostomy," Dr. Schott and coauthors write. They note that about two-thirds of patients were discharged home from the hospital, with or without home health care – and thus may not have received care from a WOC nurse.

"Timely clinical follow-up after discharge may contribute to early identification and management of modifiable factors increasing risk for stomal or peristomal complications and thereby may decrease readmissions and subsequent ED visits," the researchers add. Other priorities include reducing the frequency of unplanned ostomy surgery and providing presurgical education for all patients undergoing an ostomy.

Source:

Journal reference:

Schott, L., et al. (2022) Characteristics, Hospital Length of Stay, and Readmissions Among Individuals Undergoing Abdominal Ostomy Surgery. Review of a Large US Healthcare Database. Journal of Wound Ostomy and Continence Nursing. doi.org/10.1097/WON.0000000000000922.

Mon, 28 Nov 2022 10:00:00 -0600 en text/html https://www.news-medical.net/news/20221129/Study-reports-high-rates-of-complications-rehospitalizations-among-patients-undergoing-abdominal-ostomy-surgery.aspx
Killexams : Study finds which micronutrients benefit cardiovascular health more than others

Healthy diets are rich in antioxidants like amino acids, omega-3 fatty acids and vitamin C, but exactly how beneficial these micronutrients are for cardiovascular health has long been controversial.

Researchers found in the new meta analysis that omega-3 fatty acid decreased mortality from cardiovascular disease; folic acid lowered stroke risk; and coenzyme Q10, an antioxidant sometimes marketed as CoQ10 decreased all-cause mortality.

The new research has been published in the Journal of the American College of Cardiology.

Researchers systematically reviewed a total of 884 studies available to date on micronutrients taken as dietary supplements and analyzed their data. They identified several micronutrients that do reduce cardiovascular risk-as well as others that offer no benefit or even have a negative effect. More than 883,000 patients were involved in the combined studies.

"For the first time, we developed a comprehensive, evidence-based integrative map to characterize and quantify micronutrient supplements' potential effects on cardiometabolic outcomes," said Simin Liu, MD, MS, MPH, ScD, professor of epidemiology and medicine at Brown University and a principal investigator for the study. "Our study highlights the importance of micronutrient diversity and the balance of health benefits and risks."

The findings could be used as the basis of future clinical trials to study specific combinations of micronutrients and their impact on cardiovascular health, he said.

Antioxidant supplementation has long been thought to play a role in heart health. That's because these nutrients work to reduce oxidative stress, a known contributor to many cardiovascular diseases. Heart-healthy diets like the Mediterranean diet and the Dietary Approach to Stop Hypertension (DASH) feature foods that are naturally rich in antioxidants. However, results from studies of antioxidant supplements have been inconsistent-one reason why this approach hasn't yet been widely adopted in preventative cardiology.

"Research on micronutrient supplementation has mainly focused on the health effects of a single or a few vitamins and minerals," Liu said. "We decided to take a comprehensive and systematic approach to evaluate all the publicly available and accessible studies reporting all micronutrients, including phytochemicals and antioxidant supplements and their effects on cardiovascular risk factors as well as multiple cardiovascular diseases."

The researchers looked at randomized, controlled intervention trials evaluating 27 different types of antioxidant supplements. They found strong evidence that several offered cardiovascular benefit. These included omega-3 fatty acid, which decreased mortality from cardiovascular disease; folic acid, which lowered stroke risk; and coenzyme Q10, an antioxidant sometimes marketed as CoQ10, which decreased all-cause mortality. Omega-6 fatty acid, L-arginine, L-citrulline, Vitamin D, magnesium, zinc, alpha-lipoic acid, melatonin, catechin, curcumin, flavanol, genistein and quercetin also showed evidence of reducing cardiovascular risk.

Not all supplements were beneficial. Vitamin C, Vitamin D, Vitamin E and selenium showed no effect on long-term cardiovascular disease outcomes or type-2 diabetes risk. And beta carotene supplements increased all-cause mortality.

According to the researchers, the findings point to the need for more personalized, precision-based dietary interventions that involve specific combinations of beneficial supplements. Further study is needed, including large, high-quality interventional trials to investigate the long-term effects of certain micronutrients on health.

"Identifying the optimal mixture of micronutrients is important, as not all are beneficial, and some may even have harmful effects," Liu said.

Reference:

Peng An, Sitong Wan, Yongting Luo, Junjie Luo, Xu Zhang, Shuaishuai Zhou, Teng Xu, Jingjing He, Jeffrey I. Mechanick, Wen-Chih Wu, Fazheng Ren, Simin Liu, Micronutrient Supplementation to Reduce Cardiovascular Risk, Journal of the American College of Cardiology, Volume 80, Issue 24, 2022 https://doi.org/10.1016/j.jacc.2022.09.048

Thu, 08 Dec 2022 00:45:00 -0600 en text/html https://medicaldialogues.in/cardiology-ctvs/news/study-finds-which-micronutrients-benefit-cardiovascular-health-more-than-others-103694
Killexams : Medical Moment: Advanced cervical cancer on the rise, study says

(WNDU) - At one point, cervical cancer was one of the deadliest cancers in America.

But the development of a screening test helped cause death rates to drop!

Now, a new study shows the rates of advanced cervical cancer are growing again. And it’s affecting a group of women who would least expect it.

A vaccine to prevent HPV, the human papilloma virus, and a decades-old screening test, the PAP test, developed by scientist George Papanicolaou, both credited with preventing cervical cancer.

Now, researchers at UCLA studying trends in cervical cancer rates have found an increase in stage four, or advanced disease, in women over 40.

“Those women have about a 17 percent overall survival at five years,” said Robert Edwards, MD, Ob/GYN UPMC.

Dr. Edwards is a specialist in gynecologic oncology at the University of Pittsburgh. He says women in their forties and fifties can fall through the cracks when it comes to routine screening.

“They’re not old enough to have other medical conditions,” Dr. Edwards explained. “They’re too old to need contraception. So, they really don’t have any other reason to come to the doctor.”

Dr. Edwards went on to say that when the HPV vaccine is given to adolescents before they are sexually active, will help to eliminate cervical cancer. HPV is linked to more than 90 percent of all anal and cervical cancers.

The CDC recommends women start getting PAP tests at age 21 and receive a follow-up every three years. The test picks up precancers, which can be removed. Cervical cancer detected early has a five-year survival rate of over 90 percent.

UCLA researchers have found more than a three percent increase in advanced cervical cancers in women ages 30 to 40. They think rising health care costs are adding to the number of undetected cases.

Tue, 06 Dec 2022 07:38:00 -0600 en text/html https://www.wndu.com/2022/12/06/medical-moment-advanced-cervical-cancer-rise-study-says/
Killexams : Hair Loss Supplements Show Promise in New Study

Dec. 7, 2022 -- You’ve likely seen the ads for nutritional supplements, gummies, shampoos, and other nonprescription products that allegedly help stop hair loss. 

But do they work? The FDA does not regulate nutritional products, which means that manufacturers do not have to conduct or submit studies of safety and effectiveness to sell them. But a new review in a prestigious medical journal found that some of these companies have conducted trials, finding that some of the products are likely effective in helping to combat hair loss. 

The authors of the review, published online in JAMA Dermatology in November, combed the medical literature to find data on a wide variety of ingredients and approaches used in over-the-counter hair loss remedies. They came up with thousands of articles, but only 30 met the criteria for objectively looking at their effectiveness. 

The supplements that seemed to offer some potential benefit included the brands Lambdapil, Nourkrin, Nutrafol, Omni-Three, and Viviscal; capsaicin and isoflavone capsules; omega-3s and omega-6s with antioxidants; apple nutraceutical; the Chinese herbal extracts of total glucosides of paeony (Peony) and compound glycyrrhizin (licorice) tablets; zinc; tocotrienol; and pumpkin seed oil.

“For patients that are highly motivated and eager to try this, we’re hoping that this systematic review serves as a foundation to have a conversation,” with a dermatologist, says study co-author Arash Mostaghimi, MD, MPH, assistant professor of dermatology at Harvard Medical School.

Mostaghimi says he was surprised that he and his colleagues found evidence of effectiveness for the supplements but that he’s still skeptical that they work as consistently as described or as well as described, given that they were unable to find any negative studies.  (The studies they did find also had many flaws, including small numbers of patients, studying different kinds of hair loss in the same trial, a lack of a control group, and self-reported perception of hair loss.)

They did not find any safety issues with any of the supplements, with the exception of biotin. 

“The FDA has warned against biotin supplementation because it can interfere with some laboratory testing such as troponin and hormonal tests,”  Mostaghimi and his co-authors write in the analysis.

Eva Simmons-O’Brien, MD, a dermatologist in Towson, MD, who often recommends supplements as an additional treatment to prescription products for hair loss, says she also cautions against biotin use. There are some misperceptions about what it can do, she says. For instance, it won’t grow new hair, but it can help strengthen the new hairs that grow as a result of other therapies.

The review is important because “it basically kind of vindicates what some of us have been doing for a number of years in terms of treating hair loss,” she says. “It should hopefully make it more commonplace for dermatologists to consider using nutritional supplements as an adjuvant to treating hair loss." 

Lynne J. Goldberg, MD, professor of dermatology, pathology, and laboratory medicine at the Boston University Chobanian and Avedisian School of Medicine, says the review will be helpful because many patients take hair loss supplements and want to know if they are safe and effective. 

The study “points out what the problems are, it talks about what the individual ingredients are and what they do, what the problems are, and it concluded that some people may find these helpful. Which is exactly what I tell my patients,” says Goldberg, who is also director of the Hair Clinic at Boston Medical Center.

The review begins with a look at saw palmetto (Serenoa repens), a botanical compound thought to block the action of 5-alpha reductase, which converts testosterone to dihydroxytestosterone (DHT). DHT is involved in male and female pattern hair loss (known as androgenic alopecia or AGA). The drug finasteride works in a similar way. Saw palmetto appears to stabilize hair loss, “although its effect is likely less than that of finasteride,” write the authors. They also note that side effects associated with finasteride, such as sexual dysfunction, were also observed with saw palmetto, “but to a lesser extent.”

Pumpkin seed oil, which also blocks 5-alpha reductase, may also be effective and an alternative to finasteride, they say. 

Products containing extracts from sharks and mollusks, including Viviscal and Nourkrin, are thought to decrease hair loss by providing essential nutrients to thinning hair. Those supplements appeared effective in increasing hair counts in men and women, but studies were funded by the manufacturer and were not well controlled, said the study authors. Side effects with Viviscal also included bloating.

Multi-ingredient supplements such as Nutrafol and Lambdapil seemed to have some effectiveness, but each of the studies was flawed in some way, say Mostaghimi and his colleagues. 

Hair loss is a complicated condition and ultimately requires multiple solutions, say dermatologists. 

Simmons-O’Brien says that when evaluating patients with hair loss, she runs tests to determine if there is anemia or a thyroid issue or deficiencies in vitamins or minerals or other nutritional deficiencies, asks about diet and styling practices, and takes a scalp biopsy. She may recommend supplementation based on those findings, she says. 

Goldberg says some of her patients prefer to steer clear of prescription medications. She might recommend supplements in those cases but tells patients that they aren’t well-studied and that it can be hard to tell if they are working, and in some cases, the hair loss might resolve in a few months anyway. 

But, she adds, “if you have the money and you want to take these pills and you’re not taking too much, that’s fine.”

“As a hair loss specialist, my job is to treat the patient at their level, in their framework, in their comfort zone," says Goldberg.  

Mostaghimi says he understands why people turn to supplements. 

“I believe if we had better and more effective treatments for hair loss of all types, then people wouldn’t be using these supplements or going to more natural therapeutics,” he says. 

Wed, 07 Dec 2022 05:45:00 -0600 en text/html https://www.webmd.com/skin-problems-and-treatments/hair-loss/news/20221207/hair-loss-supplements-show-promise-new-study
Killexams : GOLDSTEIN: Medical wait times in Canada this year longest on record Patients in stretchers waiting to be admitted are shown along a hallway at the emergency department in the Windsor Regional Hospital Met campus, Jan. 23, 2018. © Provided by Toronto Sun Patients in stretchers waiting to be admitted are shown along a hallway at the emergency department in the Windsor Regional Hospital Met campus, Jan. 23, 2018.

While the federal and provincial governments squabble over health care funding, Canadians are facing the longest medical wait times for treatment ever recorded.

A new study by the Fraser Institute which has tracked this data since 1993, reports that the median wait time for treatment in Canada this year across 12 medical specialties was 27.4 weeks, surpassing last year’s 25.6 weeks and 195% higher than 9.3 weeks in 1993.

Medical wait times are defined as the time it takes for the referral of a patient by a general practitioner to the start of treatment by a specialist for medically-necessary elective care.

Elective treatment does not mean these procedures are minor, optional, unimportant or can be delayed indefinitely.

It simply means they are scheduled in advance — everything from heart and brain surgery to treatment for cancer — as opposed to emergency care.

As the study notes, “research has repeatedly shown that wait times for medically necessary treatment are not benign inconveniences” and can lead to increased pain, suffering and mental anguish, lower the chances of full recovery and in the most severe cases result in permanent disability and death.

“Crucially, physicians report that their patients are waiting over six weeks longer for treatment (after seeing a specialist) than what they consider to be clinically reasonable.”

Bacchus Barua, co-author of the study, “Waiting Your Turn: Wait Times for Health Care in Canada, 2022” said while the impact of COVID-19 on Canada’s health care system has been a contributing factor in lengthening wait times, it’s not the root cause.

“Previous results revealed that patients waited an estimated 20.9 weeks for medically necessary elective care in 2019 — long before the pandemic started,” he said.

A Fraser Institute study in 2020 found that Canada has the longest medical wait times of 10 comparable industrialized countries with universal health care systems who are members of the Organization for Economic Co-operation and Development and track comparable data.

“Excessively long wait times remain a defining characteristic of Canada’s health care system,” said study co-author Mackenzie Moir.

This year, the shortest median wait time was in Ontario at 20.3 weeks while the longest was in P.E.I. at 64.7 weeks.

Median wait times in the other provinces were, in ascending order, 25.8 weeks in B.C.; 29.4 weeks in Quebec; 30.1 weeks in Saskatchewan; 32.1 weeks in Newfoundland and Labrador; 33.3 weeks in Alberta; 41.3 weeks in Manitoba; 43.3 weeks in New Brunswick and 58.2 weeks in Nova Scotia.

Wait times went up in every province compared to last year except for B.C. and Saskatchewan where they declined slightly.

Median wait times nationally were longest for neurosurgical (brain) procedures at 58.9 weeks, shortest for radiation treatments at 3.9 weeks.

Canadians waiting for diagnostic procedures faced a median wait time of 4.9 weeks for ultrasounds, 5.4 weeks for CT scans and 10.6 weeks for MRIs.

The study estimates that nationally, Canadians are waiting for 1.2 million medical procedures this year, down slightly from 1.4 million in 2021.

The data for the study was supplied by 975 doctors across the country surveyed from Jan. 10 to Sept. 15.

While the findings are consistent with previous Fraser Institute studies on medical wait times, the authors note that because the survey covered an extended period of time and the response rate was lower than in previous years, the findings should be interpreted with some caution.

Thu, 08 Dec 2022 02:13:45 -0600 en-CA text/html https://www.msn.com/en-ca/health/medical/goldstein-medical-wait-times-in-canada-this-year-longest-on-record/ar-AA153rQf
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