Free download link of AZ-120 practice test and PDF Questions files

killexams.com Study Guide are the must for transferring the Microsoft AZ-120 exam. We all have gathered true test AZ-120 questions, which usually are updated along with especially replica through the real exam, plus checked by sector specialists. Those men and women who do not really have time to get you to research AZ-120 ebooks, just sign up and download quickest AZ-120 Exam Cram and get searching forward to examination.

Exam Code: AZ-120 Practice test 2022 by Killexams.com team
AZ-120 Planning and Administering Microsoft Azure for SAP Workloads

The content of this test was updated on July 21, 2020. Please download the test skills outline below to see what changed.
Migrate SAP Workloads to Azure (10-15%)
Design an Azure solution to support SAP Workloads (20-25%)
Build and deploy Azure for SAP Workloads (35-40%)
Validate Azure infrastructure for SAP Workloads (10-15%)
Operationalize Azure SAP architecture (10-15%)

Migrate SAP Workloads to Azure (10-15%)
Create an inventory of existing SAP landscapes
 network inventory
 security inventory
 computing inventory
 operations system inventory
 resiliency and availability inventory
 SAP Database Inventory
 SAP Landscape architecture
 SAP workload performance SLA and metrics
 migration considerations
Design a migration strategy
 certified and support SAP Hana hardware directory
 design criteria for Tailored Datacenter Integration (TDI) v4 and v5 solutions
 databox with import and export
 HANA System Replication (HSR)
 ASR for SAP
 backup and restore methods and solutions
 infrastructure optimization for migration
Design an Azure Solution to Support SAP Workloads (20-25%)
Design a core infrastructure solution in Azure to support SAP workloads
 network topology requirements
 security requirements
 virtual or bare metal
 compute
 operating system requirements
 support SAP version
 storage requirements
 proximity placement group
 infrastructure requirements
Design Azure infrastructure services to support SAP workloads
 backup and restoration requirements
 SLA/High Availability
 data protection (EFS, LRS/GRS, Availability Zones)
 compliance
 monitoring
 licensing
 application interfaces
 dependencies
Design a resilient Azure solution to support SAP workloads
 HA models supported in HANA (N+N, N+0 and N+1)
 application servers
 SAP Central services
 availability sets
 availability zones
 Disaster Recovery (DR) with Hero Regions
 Database HA
Build and Deploy Azure for SAP Workloads (35-40%)
Automate deployment of Virtual Machines (VMs)
 Azure Resource Manager (ARM) template
 automated configuration of VM
 scripting with automation tools, including script development, script modification, and deployment dependencies
Implement and manage virtual networking
 IDS/IPS for Azure
 routing fundamentals
 subnetting strategy
 isolation and segmentation for SAP landscape
Manage access and authentication on Azure
 custom domains
 Azure AD Identity Protection
 Azure AD join
 enterprise state roaming
 conditional access policies
 Role-based access control (RBAC)
 service principal
 Just in time access
Implement and manage identities
 Azure AD Connect
 AD Federation and single sign-on
 LDAP/Kerberos/SSH
 Linux VMs Active Directory domain membership mechanism
Monitor SAP workloads on Azure
 Azure Enhanced Monitoring Extension for SAP workloads
 Azure Monitors
 workspaces & metrics
Build & Deploy HA/DR infrastructure for SAP products
 ASCS/SCS deployments on Linux & Windows using either of the 4 supported
methodologies (SOFS with S2D, NetApp, Azure Files Premium, 3rd Party products that present a device as iSCS to OS)
 HA/DR scenarios for SAP HANA
 HA/DR scenarios for other RDBMS platforms
 HA for non-NetWeaver Products like IdM, SBOP BI/DS
 Where to use load balances & troubleshooting connectivity
Validate Azure Infrastructure for SAP Workloads (10-15%)
Perform infrastructure validation check
 JMeter, Avalanche for Mobility Services, Load Runner
 test implementation for SAP workloads
 verify network performance and throughput
 verify storage
 HWCCT (HANA)
 FIO and/or DD (AnyDB)
Perform operational readiness check
 backup and restore
 High Availability checks
 failover test
 DR test
 print test
Operationalize Azure SAP Architecture (10-15%)
Optimize performance
 SAP workloads on Azure using ABAPmeter
 storage structure
 SAP workloads on Azure support pre-requisites
 scheduled maintenance for planned outages
 recovery plan for unplanned outages
 SAP application and infrastructure housekeeping (i.e. snapshots on OS volumes)
 bandwidth adjustment for ExpressRoute
 IPtables and GlobalReach for HANA Large Instances (HLI)
Migrate SAP workloads to Azure
 migration strategy
 Azure Site Recovery (ASR)
 private and public IP addresses, network routes, network interface, subnets, and virtual network
 storage configuration
 source and target environments preparation
 backup and restore of data
Migrate SAP Workloads to Azure (10-15%)
Create an inventory of existing SAP landscapes
 network inventory
 security inventory
 computing inventory
 operations system inventory
 resiliency and availability inventory
 SAP Database Inventory
 SAP Landscape architecture
 SAP workload performance SLA and metrics
 migration considerations
Design a migration strategy
 certified and support SAP Hana hardware directory
 design criteria for Tailored Datacenter Integration (TDI) v4 and v5 solutions
 databox with import and export
 HANA System Replication (HSR)
 ASR for SAP
 backup and restore methods and solutions
 infrastructure optimization for migration
Design an Azure Solution to Support SAP Workloads (20-25%)
Design a core infrastructure solution in Azure to support SAP workloads
 network topology requirements
 security requirements
 virtual or bare metal
 compute
 operating system requirements
 support SAP version
 storage requirements
 proximity placement group
 infrastructure requirements
Design Azure infrastructure services to support SAP workloads
 backup and restoration requirements
 SLA/High Availability
 data protection (EFS, LRS/GRS, Availability Zones)
 compliance
 monitoring
 licensing
 application interfaces
 dependencies
Design a resilient Azure solution to support SAP workloads
 HA models supported in HANA (N+N, N+0 and N+1)
 application servers
 SAP Central services
 availability sets
 availability zones
 Disaster Recovery (DR) with Hero Regions
 Database HA
Build and Deploy Azure for SAP Workloads (35-40%)
Automate deployment of Virtual Machines (VMs)
 Azure Resource Manager (ARM) template
 automated configuration of VM
 scripting with automation tools, including script development, script modification, and deployment dependencies
Implement and manage virtual networking
 IDS/IPS for Azure
 routing fundamentals
 subnetting strategy
 isolation and segmentation for SAP landscape
Manage access and authentication on Azure
 custom domains
 Azure AD Identity Protection
 Azure AD join
 enterprise state roaming
 conditional access policies
 Role-based access control (RBAC)
 service principal
 just in time access
Implement and manage identities
 Azure AD Connect
 AD Federation and single sign-on
 LDAP/Kerberos/SSH
 Linux VMs Active Directory domain membership mechanism
Monitor SAP workloads on Azure
 Azure Enhanced Monitoring Extension for SAP workloads
 Azure Monitors
 workspaces & metrics
Validate Azure Infrastructure for SAP Workloads (10-15%)
Perform infrastructure validation check
 JMeter, AvalanchAvalanche for Mobility Services, Load Runner
 test implementation for SAP workloads
 verify network performance and throughput
 verify storage
 HWCCT (HanaHANA)
 FIO and/or DD (AnyDB)
Perform operational readiness check
 backup and restore
 high availability checks
 failover test
 DR test
 print test
Operationalize Azure SAP Architecture (10-15%)
Optimize performance
 SAP workloads on Azure using ABAPmeter
 storage structure
 SAP workloads on Azure support pre-requisites
 scheduled maintenance for planned outages
 recovery plan for unplanned outages
 SAP application and infrastructure housekeeping (i.e. snapshots on OS volumes)
 bandwidth adjustment for ExpressRoute
 IPtables and GlobalReach for HANA Large Instances (HLI)
Migrate SAP workloads to Azure
 migration strategy
 Azure Site Recovery (ASR)
 private and public IP addresses, network routes, network interface, subnets, and virtual
network
 storage configuration
 source and target environments preparation
 backup and restore of data

Planning and Administering Microsoft Azure for SAP Workloads
Microsoft Administering test
Killexams : Microsoft Administering test - BingNews https://killexams.com/pass4sure/exam-detail/AZ-120 Search results Killexams : Microsoft Administering test - BingNews https://killexams.com/pass4sure/exam-detail/AZ-120 https://killexams.com/exam_list/Microsoft Killexams : An Unstoppable Force Meets an Immovable Object: Microsoft to Fight FTC Over Activision Deal

Monday, December 12, 2022

If anyone knows the workings of Washington’s antitrust machinery, it’s Microsoft’s president, Brad Smith, who served as the company’s general counsel during the late 1990s, when the Justice Department sued Microsoft in one of the most famous monopolization cases in modern times.

So, it is hardly surprising that Smith has been trying to “fix it first” in the past few months, making deals and announcing commitments designed to make Microsoft’s $ 68.7 billion acquisition of Activision Blizzard more palatable to antitrust regulators.

Microsoft, valued at $2.3 trillion and the nation’s most famous monopolist, is proposing the largest deal in its history, and in the history of the video game industry, to acquire the powerhouse publisher of some of the most popular video games, including Call of DutyCandy Crush SagaWorld of Warcraft, Overwatch, Guitar Hero, and others, instantly making Microsoft the third largest gaming company by revenue, behind China’s Tencent and Japan’s Sony. Although most games can be played on computers and smartphones, Microsoft also makes the Xbox, a premium gaming console that competes with Sony’s PlayStation and, to a lesser extent, Nintendo’s Switch.

Antitrust scrutiny of this deal was all but guaranteed, given Microsoft’s antitrust reputation, the size of the transaction, and a political climate in which the Biden administration’s antitrust regulators have vowed to scrutinize mergers more rigorously, particularly in high-tech industries. Additionally, Microsoft already publishes MinecraftHalo, and other popular games, in part thanks to its latest March 2021 acquisition of ZeniMax Media. There is plenty of time for a thorough antitrust investigation. The merger agreement, signed in January 2022, provided for closing in July 2023.

As the FTC and the antitrust world examined the deal, a consensus of sort seemed to emerge that the “overlaps” in game titles alone would not be enough to threaten the acquisition. But Sony complained publicly that the deal would allow Microsoft to make Call of Duty, the most played game on PlayStation, exclusive to Xbox, and that the three years of access offered by Microsoft was wholly inadequate. Other commentators pointed to the Commission’s newly found interest in labor markets raised concerns that a Microsoft-Activision will be overly powerful as an employer of creatives and coders that make video games.

Mr. Smith then went to work to fix it first, before the FTC’s decision about whether to challenge the deal. He made a deal with Nintendo to make Call of Duty available to the Switch console if the deal goes through and offered the same deal to Sony. He got sign-off on the deal from the Communications Workers of America. He conducted a public relations and charm offensive, making clear that Microsoft would agree to court-ordered conditions.

All to no avail. The FTC filed an administrative complaint on December 8 challenging the legality of the transaction, alleging likely harm to competition in three markets: the “high performance console” market, the “multi-game content library subscription services” market, and the “cloud gaming subscription services” market. What these market definitions all have in common is they describe channels of distribution.

The complaint, therefore, challenges the vertical, not horizontal, effects of the Activision acquisition. In the FTC’s view, ownership of the Activision’s content would give Microsoft the power to control the means by which players consume games. By withholding or degrading Microsoft-Activision game titles from rival console makers (Sony) or competing game subscription or cloud streaming services, the merged entity could substantially impair competition in those markets.

Having shown their hand, it is clear that Mr. Smith could never have “fixed it first” for the majority of the Commission intent on expanding merger law.

The Microsoft-Activision merger is the perfect vehicle—both optically and legally—to test the capacity of U.S. antitrust law to deal with competitive threats that arise from vertical integration. The Commission has turned out to be an unstoppable force.

But the law may be on Microsoft’s side, if ever so slightly, and the Commission is just as likely to find itself before a judge willing to accept novel arguments about competitive effects as one who isn’t. Knowing this, Mr. Smith commented (on the 42nd anniversary of the death of John Lennon) that, having tried to “give peace a chance,” Microsoft intends to fight the FTC as far as necessary. An immovable object.

It will be interesting to see whether the collision of the unstoppable force with the immovable object will render merger law any more flexible and modern than it is today, as Chairman Kahn and her colleagues clearly hope.

Mon, 12 Dec 2022 03:40:00 -0600 en text/html https://www.natlawreview.com/article/unstoppable-force-meets-immovable-object-microsoft-to-fight-ftc-over-activision-deal
Killexams : FTC’s Microsoft Lawsuit Treads New Ground in Targeting Vertical Expansions

If there were doubts about the Federal Trade Commission’s determination to follow through on its aggressive antitrust stance against Big Tech, last week’s events might squelch them.

On Thursday, the FTC swung wide, suing Microsoft for its $69 billion acquisition of game developer Activision, and commencing arguments to block Meta from absorbing virtual reality company Within Unlimited.

Tue, 13 Dec 2022 08:48:00 -0600 en text/html https://www.law.com/legaltechnews/2022/12/13/ftcs-microsoft-lawsuit-treads-new-ground-in-targeting-vertical-expansions/?slreturn=20221114050843
Killexams : The Stakes Behind the F.T.C.’s Bid to Block Microsoft’s Big Deal

The Biden administration yesterday took its boldest step yet in challenging the reach of tech giants when the F.T.C. sued to block Microsoft’s $69 billion takeover of Activision Blizzard.

The move is meant to prevent Microsoft from consolidating power in the video-game industry, but it also represents something bigger. The F.T.C. under Lina Khan wants to rewrite the nation’s antitrust approach to Big Tech and mergers.

The F.T.C. warned about serious blows to competition. Activision, the publisher of hit games like Call of Duty and Candy Crush, has almost 370 million active users each month. Putting it together with Microsoft, which owns the Xbox platform, would run the risk that popular titles would be withheld from rival platforms, according to the agency.

Microsoft has argued that doing so would not make economic sense, and recently agreed to make Call of Duty available to Nintendo for 10 years. (It has extended a similar offer to Sony.) But the F.T.C. is leery of such promises: It cited Microsoft making two titles exclusive to its platforms, despite pledging to European authorities that it had no incentive to do so.

The lawsuit is Microsoft’s biggest challenge in Washington in two decades, when the Justice Department sued the company over its dominance of personal computing. Since then, Microsoft has sought to paint itself as a good corporate citizen, standing with the government on issues like providing A.I. to the Pentagon and arguing against other companies’ closed app ecosystems.

Microsoft pledged to fight this case. “While we believed in giving peace a chance, we have complete confidence in our case and welcome the opportunity to present our case in court,” Brad Smith, its president, said in a statement.

Washington may not be Microsoft’s only battlefield, however. Regulators in both the European Union and Britain have already weighed in on the Activision deal, and may be emboldened by the F.T.C.’s aggressive approach.

It’s the biggest test yet of Ms. Khan’s effort to overhaul antitrust law. In latest decades, courts have tended to approve so-called vertical mergers, like the Activision deal, that unite two related companies in an industry, rather than putting together direct competitors.

But Ms. Khan, the F.T.C.’s chair, has argued that approach ignores the effects of vertical mergers on issues like innovation, particularly as big companies get even bigger. (Also yesterday, opening arguments began in the F.T.C.’s lawsuit seeking to block Meta, the parent company of Facebook, from buying the maker of a virtual-reality fitness app, on similar grounds as the Activision suit.)

Ms. Khan has acknowledged that the strategy may not win in the courts every time. But she has defended filing long-shot lawsuits if they expand the boundaries of competition regulation, including by persuading Congress to change antitrust law.

Still, some critics are unconvinced: “Whatever the agency is doing doesn’t really seem to be rattling big tech, which seems to realize the legal scrutiny is part of the cost of doing business,” writes Jessica Lessin, the founder of the tech news publisher The Information.

Saudi Arabia and China strike a strategic partnership. The agreement, made during the Chinese leader Xi Jinping’s visit to the Middle East, underscores the growing ties between Beijing and Riyadh. Saudi Arabia’s de facto ruler, Crown Prince Mohammed bin Salman, has been especially eager to diversify his country’s allies beyond the United States.

The W.N.B.A. star Brittney Griner lands in the U.S. after a prisoner swap with Russia. Griner, who had been held for 10 months, was released in exchange for the convicted arms dealer Viktor Bout, nicknamed the “Merchant of Death.” White House officials acknowledged that the deal raised the risk of prominent Americans being detained as political prisoners.

The S.E.C. requires more corporate disclosure about crypto risks. The regulator issued a new rule that will force companies to list their cryptocurrency holdings and exposure to developments like FTX’s implosion in public filings. Meanwhile, text messages between crypto executives show their fear about the consequences of FTX’s downfall.

Exxon Mobil plans to spend $50 billion on stock buybacks. The move, which will expand a repurchase program from $30 billion, underscores the oil giant’s focus on channeling profits from high energy prices to shareholders. But it also defies the wishes of President Biden and others that such a windfall should instead be spent on new exploration.

Senator Kyrsten Sinema leaves the Democratic Party. The Arizona lawmaker said this morning that she was registering as an independent, after clashing repeatedly with Democratic leaders on a variety of policies. It appears that she will still caucus with Democrats, helping them retain control of the upper chamber, but she may feel freer to oppose some of their bills.

China this week lifted many of its pandemic restrictions, easing elements of its zero-Covid policy. But the abruptness of the U-turn, coupled with a resurgence in Covid cases and underlying economic and geopolitical problems, won’t make things any easier for global companies operating in the country. Here’s why.

Covid may be ripping through the population. China is reportedly underplaying the scale of a Covid surge, after suddenly lifting requirements for mass testing and lockdowns. That would mean that normality is a long way off, with the population having little built-in immunity and many older citizens still unvaccinated (or having received domestic vaccines that are less effective than Western ones). “Overall, it’s a good thing that they’re reopening and in such a speedy manner,” said Yanzhong Huang, a health expert at the Council on Foreign Relations. “But the way they handled it is puzzling. They switched from one extreme to another without investing in any preparation efforts.”

The economy is expected to suffer for longer. November was the worst month for Chinese trade since the start of the pandemic, while the property sector, which has accounted for about a quarter of economic output over the past decade, is still lagging. Double-digit economic growth rates that were typical in China are unlikely to come back soon.

The rise in infections also means that factories will probably see higher absenteeism rates and that cautious consumers will be unlikely to resume spending.

“The economic bounce that will happen once the virulence of Covid is spent and people’s confidence returns may not be as sharp,” said George Magnus, the former chief economist at UBS and an associate at Oxford University’s China center.

Beijing is maintaining an iron grip. The sudden shift on Covid, without any mitigating measures, is the latest sign that China’s leader, Xi Jinping, has almost absolute control on the country. Scores of Western companies in China were already reconsidering their operations there, after Mr. Xi elevated ideology and national security above economic growth and the private sector.

And China’s geopolitical fight with the West remains unresolved, so the balancing act for companies operating in both against the backdrop of pressure to “decouple” the economies won’t soon end.


Back in 2009, Pimco coined the term “New Normal” to describe how the global economy was probably forever changed by the financial crisis. Now the strategist and economist Mohamed El-Erian — then Pimco’s C.E.O. and now the chief economic adviser at Allianz — thinks that a newer mix of geopolitical tension, pandemic and inflation is permanently changing the global economy, again.

He spoke with Times Opinion’s Ezra Klein on this new phase. Here are some takeaways from their conversation.

Don’t expect a return to a prepandemic world. The biggest mistake forecasters are making is to assume the economy will eventually revert to its 2020 state, Mr. El-Erian told Mr. Klein. Instead, the U.S.’s move to shift its supply chain away from China over deepening political tensions, as well as the realities of addressing climate change, will lead to a period of sustained inflation.

The world we inhabit now will be a lot less predictable, he said. That will require more redundancy planning in everyday life and in business, which will result in rising costs, and require a change in mind-set.

“Unless we do that, unless we open to the possibility that we’re living in a much more fluid world, we may end up undershooting on economic, social and institutional objectives that are really important, not just for this generation, but for the future one,” Mr. El-Erian said.

You can listen to the full episode here.


Yesterday, we told you about a new fund-raising round for Juno, which focuses on providing affordable health care to underserved communities, involving Serena Williams’s firm, Serena Ventures.

But there is a detail in the back story that deserves telling: The deal was co-led by Next Ventures.

If you haven’t heard of Next Ventures, you should. It is led by Lance Armstrong, the former pro cyclist-turned-investor and podcaster. Next Ventures, which he started in 2019, has made more than a dozen investments, including in the fitness tracker Oura Ring and Outside magazine.

Mr. Armstrong got into venture capital when he was still a professional cyclist, as an early limited partner in the firm Lowercase Capital — which in turn made him a very early investor in Uber.

Next Ventures has focused on investments in the health and wellness space. Those now include Juno, which was started by Dr. Akili Hinson. “We have one health care system if you are Black, brown or poor, and then there’s another health system for everyone else,” Dr. Hinson said.

Deals

  • How Salesforce’s C.E.O., Marc Benioff, reportedly soured on Slack, even before closing the $28 billion deal to buy the messaging app. (The Information)

  • Unilever is reportedly weighing the sale of ice cream brands like Breyers and Klondike — but not Ben & Jerry’s — for around $3 billion (Bloomberg)

  • Keurig Dr Pepper will invest $863 million for a 30 percent stake in Nutrabolt, the maker of energy drinks like C4, months after dropping an effort to buy Bang Energy. (Bloomberg)

Policy

  • Oil company executives remained privately skeptical of a global shift to renewable energy even as they publicly championed such moves, according to documents obtained by House lawmakers. (WaPo)

  • President Biden announced a $36 billion bailout for the pensions of over 350,000 union workers and retirees. (NYT)

  • Lawmakers accused Dan Snyder, the owner of the Washington Commanders, of impeding investigations into sexual harassment claims against himself and other team executives. (NYT)

Best of the rest

We’d like your feedback! Please email thoughts and suggestions to dealbook@nytimes.com.

Thu, 08 Dec 2022 22:44:00 -0600 en text/html https://www.nytimes.com/2022/12/09/business/dealbook/ftc-microsoft-activision-khan.html
Killexams : The FTC's Effort to Block Microsoft's Activision Acquisition Will Test Biden's Antitrust Legacy

Photo: Ethan Miller (Getty Images)

It’s official. After months of rumors, the Federal Trade Commission this week voted 3-1 in favor of suing to block Microsoft’s estimated $69 billion acquisition of video game giant Activision Blizzard.

The forthcoming legal battle represents the most significant antitrust challenge from the Biden-era FTC to date that has, up until now, had few tangible victories to back up its progressive, anti-monopolist rhetoric. The challenge’s success or failures could play a large factor in determining whether or the Biden administration can live up to its image as an aggressive antitrust maverick.

Read more

In a press release Thursday, the FTC argued the acquisition, if allowed to occur, would let Microsoft suppress competitors to its own Xbox gaming console and its growing cloud gaming business. Microsoft, according to the FTC, had already demonstrated a pattern of acquiring big name game studios like Bethesda only to make their titles exclusive to Microsoft’s platform.

“Microsoft has already shown that it can and will withhold content from its gaming rivals,” FTC Bureau Director of Competition Holly Vedova said in a statement. “Today we seek to stop Microsoft from gaining control over a leading independent game studio and using it to harm competition in multiple dynamic and fast-growing gaming markets.”

The FTC vote comes just days after Microsoft announced it intended to bring Activision’s massively popular Call of Duty franchise to Steam and Nintendo consoles. Sony, Microsoft’s primary competitor in the console gaming sector, shot down an offer to keep the franchise on Playstation for 10 years. Sony has opposed the acquisition outright and claimed the deal would have, “major negative implications for gamers and the future of the gaming industry.”

Microsoft Vice Chair and President Brad Smith commented publicly on the FTC’s decision and expressed confidence in the acquisition which he believes would, “expand competition and create more opportunities for gamers and game developers.”

“We have been committed since Day One to addressing competition concerns, including by offering earlier this week proposed concessions to the FTC,” Smith said on Twitter. “While we believe in giving peace a chance, we have complete confidence in our case and welcome the opportunity to present it in court.”

The FTC’s vote to block the Activision acquisition was praised by consumer advocacy groups, some of which had spent months urging regulators to take a more proactive approach towards large acquisition attempts.

“Microsoft’s attempt to acquire Activision is unlawful, and it’s not particularly close,” American Economic Liberties Project Executive Director Sarah Miller said in a statement sent to Gizmodo. “The FTC made the right call. Microsoft’s flurry of last-minute promises to not abuse the market power that they’d gain from this deal reinforce its underlying illegality.”

The agency’s decision also received praise from Massachusetts Senator Elizabeth Warren, who’s previously introduced antitrust legislation targeting growing consolidation across multiple industries.

“Corporate monopolies have had free rein to hike prices and harm workers, but now the Biden admin is committed to promoting competition,” Warren said.

More from Gizmodo

Sign up for Gizmodo's Newsletter. For the latest news, Facebook, Twitter and Instagram.

Click here to read the full article.

Thu, 08 Dec 2022 12:06:00 -0600 en-US text/html https://news.yahoo.com/ftcs-effort-block-microsofts-activision-224500875.html
Killexams : The Biden Administration’s New STEM Initiative: What Will It Mean for K-12 Schools?

A new Biden administration initiative aims to expand access to science, technology, engineering, math, and medical career fields through partnerships with universities, STEM companies, and nonprofit organizations.

The White House announced a new “STEMM” (adding an extra M to the well-known acronym to include medical fields) national vision and strategy during the Dec. 12 Summit on STEMM Equity and Excellence. The initiative outlines five action items that the government and its industry and education partners will take to Strengthen STEMM equity and access across the country and involves over $1.2 billion in work and investments from the federal government, industry leaders, and nonprofit organizations, according to a fact sheet.

“The time has come to work boldly, with urgency, together to open the doors of opportunity across these five action areas,” Alondra Nelson, the principal deputy director for science and society at the White House’s office of science and technology policy, said during the summit.

The five action items the federal government plans to put in place include:

  • Provide holistic and lifelong support for students, teachers, workers, and communities to participate in, and contribute to, science and technology;
  • Address STEMM teacher shortages by recruiting and retaining teachers and improving teacher respect;
  • Close STEMM funding gaps and support students, researchers, and communities that have historically been excluded from access to STEMM resources;
  • Root out systemic bias, inaccessibility, discrimination, and harassment in classrooms, laboratories, and workplaces;
  • And promote culture and systems of accountability across science and technology communities, workplaces, and education fields.

The idea is that the action items will provide students from all backgrounds with the opportunities they need to access and excel in STEMM fields. For the STEMM workforce to reflect societal demographics by 2030, the number of women in those jobs would need to double, the number of Black people would need to more than double, and the number of Hispanic people would need to triple, according to a report from the National Science Foundation.

“People talk about those [people] as the missing millions, the people who have these enormous contributions to make but who can’t yet find pathways into STEMM jobs,” said Arati Prabhakar, the chief adviser to the president for science and technology and the director of the office of science and technology policy.

Federal and private partnerships to expand opportunities in high-needs communities

Within each of the five action areas identified through the initiative are specific programs and steps the federal government and industry leaders are taking to Strengthen STEMM opportunities.

The White House highlighted federal programs with the U.S. Patent and Trade Office, NASA, and the National Science Foundation to fund and provide work-based and hands-on learning opportunities for students from high-needs areas and varying backgrounds.

The U.S. Department of Education also plans to focus on recruiting teachers and training teachers in STEMM, while also developing equitable pathways for careers for students, said Joaquin Tamayo, the chief of staff for the department’s deputy secretary, Cindy Marten. The department wants all students to feel that they belong in STEMM classrooms and careers, he said.

“We’re experiencing right now, particularly as we come out of the pandemic, a crisis of belonging in this country, a crisis of belonging in our classrooms, a crisis of belonging among our educators, and it’s having a serious impact,” Tamayo said.

As for private-sector work, the American Association for the Advancement of Science is partnering with the Doris Duke Charitable Foundation to bring together more than 90 companies and organizations involved in the STEMM field to be a part of the STEMM Opportunity Alliance.

The alliance will work to achieve STEMM equity and excellence across the White House’s five identified action areas by 2050. So far, the philanthropic organizations involved in the alliance have donated $4 million to its work.

Each of the 90 companies and organizations has committed to specific actions to Strengthen STEMM equity. For example, Micron, a semiconductor, memory, and storage manufacturer, and the National Science Foundation plan to invest $10 million to accelerate training of new STEMM teachers, support the retention of existing STEMM educators, and advance diversity and equity in the STEMM teacher workforce.

“We’ve got to make sure that our educator pipeline looks like the STEMM pipeline that we’re trying to create,” said April Arnzen, Micron’s senior vice president and chief people officer.

Removing systemic barriers to participation is critical

During the summit, Zach Oxendine, an engineer at Microsoft, shared how his experience navigating the school system and pursuing a career in the technology field was anything but simple.

Oxendine, originally from Rock Hill, S.C., is a member of the Lumbee Native American tribe and the son of deaf parents, who divorced when he was in elementary school. Though he always showed talent in school, he struggled to find people who believed in him.

“I often found myself in trouble at school,” Oxendine said. “And although I was deemed a bright kid by test scores and honors classes, my grades did not reflect that potential. For me, school was not a place where I always felt like I could be empowered to be my authentic self.”

Oxendine described how he faced setbacks when his family couldn’t afford the cost for him to participate in his school’s talent-identification program for students with high standardized-test scores, and he struggled to figure out how to pay for college or even envision himself in a college setting. So Oxendine joined the U.S. Air Force, where he discovered the field of technology and pursued a college degree and, later, his career in IT and engineering, eventually landing at Microsoft.

Oxendine created his own STEM youth camp for Native American students in the Southeast, specifically students who are members of the Lumbee and Catawba tribes. In his speech at the summit, Oxendine said the White House’s initiative is an important step forward for equity in STEMM and urged national and industry leaders to take the same initiative to remove barriers to STEMM fields and education.

“You see too many kids like me,” he said. “They don’t have the opportunity or the supports to access or thrive in STEMM, and STEMM pathways are far too often blocked for too many of America’s youth.”

Mon, 12 Dec 2022 06:34:00 -0600 en text/html https://www.edweek.org/teaching-learning/the-biden-administrations-new-stem-initiative-what-will-it-mean-for-k-12-schools/2022/12
Killexams : State Laws Block Access to Fentanyl Test Strip

Politicians frequently pay lip service to stopping fentanyl overdoses while continuing to prohibit things that could actually stop them or implement policies to make them less likely. The latest example comes from Iowa, where harm reduction kits can’t contain fentanyl test strips. The reason: State law classifies fentanyl test strips as drug paraphernalia, which is illegal…

The reason for these bans can be traced back to the Drug Enforcement Administration (DEA), Stat explains. Fentanyl test strips are largely illegal “thanks to a bill that most states passed in the late 1970s at the urging of the [DEA]. The law criminalized drug paraphernalia, and included devices that test the contents of illicit substances in that category.”

For more on this issue, see this policy analysis  from the Cato Institute’s Jeffrey A. Singer and the R Street Institute’s Sophia Heimowitz.

As Singer and Heimowitz point out, it’s not just drug testing devices banned under anti-paraphernalia laws but a number of other harm reduction tools, as well. “Some paraphernalia laws restrict people from purchasing or possessing clean needles and syringes, increasing the risk of infection from sharing and reusing those items,” they write. “People risk incarceration if they give out or obtain clean needles and syringes, test strips to check for dangerous additives or contaminants in drugs obtained on the black market, or materials to clean drug use equipment.

Fri, 09 Dec 2022 03:28:00 -0600 en text/html https://www.rstreet.org/2022/12/09/state-laws-block-access-to-fentanyl-test-strip/
Killexams : COVID-19 vaccinations administered in the U.S. as of December 2022, by manufacturer As of December 7, 2022, almost 392 million Pfizer-BioNTech COVID-19 vaccine doses had been administered in the United States. This statistic shows the number of COVID-19 vaccinations administered in the United States as of December 7, 2022, by manufacturer. Thu, 08 Dec 2022 10:00:00 -0600 en text/html https://www.statista.com/statistics/1198516/covid-19-vaccinations-administered-us-by-company/ Killexams : Henrico school nurses now authorized to administer naloxone

HENRICO COUNTY, Va. -- The Henrico County School Board voted Dec. 8 to approve a revision to its Health Services policy that will allow school nurses to carry and administer naloxone to students or staff members. Naloxone – also known by the brand name Narcan– is a medication that can reverse an opioid overdose, such as those from heroin, fentanyl, or prescribed opioid medications. The policy would allow nurses to administer the drug to students or staff who are experiencing a life-threatening overdose. Click here to continue practicing on Henrico Citizen.

EAT IT, VIRGINIA serves restaurant news and interviews.

Copyright 2022 Scripps Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

Fri, 09 Dec 2022 16:14:00 -0600 en text/html https://www.wtvr.com/news/local-news/henrico-school-naloxone-december-09-2022 Killexams : Mainz Biomed Announces IRB Approval and Initiation of US Pivotal FDA Clinical Study
  • ReconAAsense study examining the clinical performance of mRNA and DNA test combined with a fecal immunochemical test for early detection of advanced adenoma and colorectal cancer to enroll 15,000 subjects across the United States, results expected in 2025
  • Aims to enhance technical profile of the Mainz Biomed test to identify advanced adenomas (AA), a type of pre-cancerous polyp that can lead to colorectal cancer (CRC)
  • Study will form the basis of the data package for review by the U.S. Food and Drug Administration (FDA) to achieve marketing authorization

BERKELEY, Calif. and MAINZ, Germany, Dec. 06, 2022 (GLOBE NEWSWIRE) -- Mainz Biomed NV MYNZ ("Mainz Biomed" or the "Company"), a molecular genetics diagnostic company specializing in the early detection of cancer, announced today that it has received approval from an independent Institutional Review Board (IRB) for the protocol ReconAAsense, the Company's U.S. pivotal study to evaluate the clinical performance of its highly efficacious and easy-to-use detection test for colorectal cancer (CRC). Mainz Biomed will now initiate the study, which will form the basis of the data package to be submitted for review by the U.S. Food and Drug Administration (FDA) to achieve marketing authorization.

ReconAAsense is a prospective clinical study that will include approximately 15,000 subjects from 150 sites across the United States. The study objectives include calculating sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) in average-risk subjects for CRC and advanced adenomas (AA). 

Integral to the Company's development strategy concerning the evolution of the product's specifications is the potential to upgrade its technical profile to achieve a transformational advancement in self-administered CRC screening. To this end, Mainz Biomed recently initiated eAArly DETECT, its U.S. extension of ColoFuture, the Company's European feasibility study evaluating the integration of a portfolio of novel gene expression (mRNA) biomarkers into its next-generation product. These biomarkers have demonstrated a unique ability to identify precancerous colonic polyps and early-stage CRC (Herring et al., 2021). The eAArly DETECT study was initiated in November of 2022 and is evaluating the effectiveness of these biomarkers to enhance product specifications to extend its capability to include the detection of advanced adenomas while increasing rates of diagnostic sensitivity and specificity for colorectal cancer. Mainz Biomed expects to complete eAArly DETECT enrollment in Q1 2023 and targets reporting topline results in 1H 2023. Based on the study's outcome, Mainz Biomed will decide on the integration of the biomarkers evaluated in ColoFuture's eAArly DETECT into the ReconAAsense study.

"Given that colorectal cancer continues to be one of the deadliest forms of cancer, early detection plays a critical role in disease prevention and treatment," commented Guido Baechler, Chief Executive Officer of Mainz Biomed. "We look forward to commencing the U.S. regulatory approval process for our next-generation product and are passionate about bringing this easy-to-administer test to the U.S. In addition, we eagerly await results from the ColoFuture feasibility study, as the potential to include novel biomarkers to detect advanced adenomas will be a game changer for at-home CRC screenings."

Once enrollment commences, ReconAAsense will continue until at least 73 evaluable subjects are diagnosed with colorectal cancer, and at least 138 evaluable subjects are diagnosed with advanced adenoma. Details about the ReconAAsense study will soon be online at clinicaltrials.gov. The Company anticipates reporting results in 2025.

About Colorectal Cancer 
According to the Centers for Disease Control and Prevention (CDC), colorectal cancer (CRC) is the second most lethal cancer in the U.S. and Europe, but also the most preventable, with early detection providing survival rates above 90%. Annual testing costs per patient are minimal, especially when compared to late-stage treatments of CRC, which cost patients an average of $38,469 per year. The American Cancer Society estimated that in 2021 there were approximately 149,500 new cases of colon and rectal cancer in the US, with 52,980 resulting in death. Recent decisions by the US Food and Drug Administration (FDA) suggest that screening with stool DNA tests such as ColoAlert in the US should be conducted once every three years starting at age 45. Currently, there are 112 million Americans aged 50+, a total that is expected to increase to 157 million within 10 years and a US market opportunity of approximately $3.7 billion per year.

About Mainz Biomed NV 
Mainz Biomed develops market-ready molecular genetic diagnostic solutions for life-threatening conditions. The Company's flagship product is ColoAlert, an accurate, non-invasive and easy-to-use, early-detection diagnostic test for colorectal cancer. ColoAlert is currently marketed across Europe and the United Arab Emirates with the intention of beginning its pivotal FDA clinical study in 2022 for US regulatory approval. Mainz Biomed's product candidate portfolio also includes PancAlert, an early-stage pancreatic cancer screening test based on real-time Polymerase Chain Reaction-based (PCR) multiplex detection of molecular-genetic biomarkers in stool samples. To learn more, visit mainzbiomed.com or follow us on LinkedIn, Twitter and Facebook.

For media inquiries -
In Europe: 
MC Services AG 
Anne Hennecke/Caroline Bergmann 
+49 211 529252 20 
mainzbiomed@mc-services.eu

In the US: 
Spectrum Science 
Melissa Laverty/Valerie Enes 
+1 540 272 6465 
mainz@spectrumscience.com

For investor inquiries, please contact ir@mainzbiomed.com 

Forward-Looking Statements 
Certain statements made in this press release are "forward-looking statements" within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words such as "anticipate", "believe", "expect", "estimate", "plan", "outlook", and "project" and other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements reflect the current analysis of existing information and are subject to various risks and uncertainties. As a result, caution must be exercised in relying on forward-looking statements. Due to known and unknown risks, real results may differ materially from the Company's expectations or projections. The following factors, among others, could cause real results to differ materially from those described in these forward-looking statements: (i) the failure to meet projected development and related targets; (ii) changes in applicable laws or regulations; (iii) the effect of the COVID-19 pandemic on the Company and its current or intended markets; and (iv) other risks and uncertainties described herein, as well as those risks and uncertainties discussed from time to time in other reports and other public filings with the Securities and Exchange Commission (the "SEC") by the Company. Additional information concerning these and other factors that may impact the Company's expectations and projections can be found in its initial filings with the SEC, including its annual report on Form 20-F filed on May 5, 2022. The Company's SEC filings are available publicly on the SEC's website at www.sec.gov. Any forward-looking statement made by us in this press release is based only on information currently available to Mainz Biomed and speaks only as of the date on which it is made. Mainz Biomed undertakes no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise, except as required by law. 


© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Mon, 05 Dec 2022 18:04:00 -0600 text/html https://www.benzinga.com/pressreleases/22/12/g29968974/mainz-biomed-announces-irb-approval-and-initiation-of-us-pivotal-fda-clinical-study
Killexams : HEMS principal honored for administering life-saving CPR

Wed, 07 Dec 2022 07:44:00 -0600 en text/html https://www.herald-dispatch.com/news/hems-principal-honored-for-administering-life-saving-cpr/article_c282524e-2d9b-5156-803a-f70a067f1454.html AZ-120 exam dump and training guide direct download
Training Exams List