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A00-250 study tips - SAS Platform Administration for SAS9 Updated: 2023
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A00-250 SAS Platform Administration for SAS9
Exam Name SAS Certified Platform Administrator for SAS 9
Exam Code A00-250
Exam Duration 110 minutes
Exam Questions 70 multiple-choice and short-answer questions
Passing Score 70%
Successful candidates should be able to:
Secure the SAS configuration on each server machine.
Check status and operate servers.
Monitor server activity and administer logging.
Establish formal, regularly scheduled backup processes.
Add users and manage their access.
Establish connectivity to data sources.
Set up and secure metadata folder structures.
Administer repositories and move metadata.
Securing the SAS configuration
Secure a SAS platform configuration.
Update SAS Software
Monitoring the Status and Operation of SAS Metadata Servers
Manage metadata repositories.
Identify the properties and functionality of SAS servers.
Configure a SAS Metadata server cluster.
Monitoring, Logging, and Troubleshooting SAS Servers
Monitor SAS servers.
Administer SAS server logging and modify logging configurations.
Troubleshoot basic SAS server issues such as server availability.
Backing Up the SAS Environment
Backup and restore the SAS environment.
Manage connection profiles.
Register users and groups in the metadata.
Give users access to processing servers and data servers.
Determine when to store passwords in the metadata.
Manage internal SAS accounts.
Identify SAS server authentication mechanisms.
Administering Data Access
Register libraries and tables in the metadata.
Update table metadata.
Pre-assign a library.
Troubleshoot data access problems.
Use the metadata LIBNAME engine.
Identify how the metadata authorization layer interacts with other security layers.
Identify where, how, and to whom metadata permissions are assigned.
Determine the outcome of metadata authorization decisions.
Use metadata permissions to secure metadata.
Create and use Access Control Templates.
Promote metadata and associated content.
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SAS Platform Administration for SAS9
To support seamless access to database servers or SAS processing servers, a login for
outbound use may be defined in the metadata. An outbound login must include:
A. a userID.
B. a user ID and password.
C. a user ID and authentication domain.
D. a user ID, password, and authentication domain.
Given the definition: A SAS metadata object that pairs logins with the server definitions
where those credentials will correctly authenticate. What is being defined?
A. authentication domain
B. outbound login
C. cached credential
D. retrieved credential login
Which server does the Connection Profile allow you to connect to?
A. metadata server
B. workspace server
C. OLAP server
D. stored process server
In most deployments of the Platform for SAS Business Analytics, which type of access
requires passwords for external accounts to be stored in the metadata?
A. seamless access to the SAS datasets
B. seamless access to SAS OLAP cubes
C. seamless access to external databases
D. all of the above
How do you modify the logging levels of a server without having to restart the server?
A. Modify theRollingFileAppender.
B. Use the IOMServerAppender to specify the message.
C. Use the Server Manager plug-in to modify the logger settings dynamically.
D. Modify the logconfig.xml file.
A platform administrator needs to update service account passwords in the metadata and
configuration files. How can the platform administrator perform this configuration task?
A. Modify theRollingFileAppender.
B. Use the Server Manager plug-in.
C. Use the SAS Deployment Manager.
D. Modify the UpdatePasswords.html file.
Place the Log events in order of Diagnostic Level for severity from Highest (most
severe) to Lowest.
A. DEBUG, INFO, ERROR, WARN
B. WARN, ERROR, DEBUG, TRACE
C. ERROR, DEBUG, TRACE, WARN
D. ERROR, WARN, INFO, DEBUG
Which process does NOT create a log file by default?
A. Metadata server
B. Workspace server
D. OLAP Server
A platform administrator is working with SAS OLAP servers and wants to: - display all
OLAP servers and schemas - provide session controls - manage advanced server options
How can the platform administrator perform these tasks?
A. open the Server Monitoring OLAP Tab
B. open the Server Monitoring Servers Tab
C. use the SAS OLAP Server Monitor plug-in
D. use the SAS Server Processes plug-in
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This news release constitutes a “designated news release” for the purposes of the Company’s prospectus supplement dated December 16, 2021 to its short form base shelf prospectus dated December 14, 2021.
MONTREAL, Oct. 13, 2023 (GLOBE NEWSWIRE) -- Theratechnologies Inc. (“Theratechnologies” or the “Company”) (TSX: TH) (NASDAQ: THTX), a biopharmaceutical company focused on the development and commercialization of innovative therapies, today announced results from a study evaluating an intramuscular (IM) method of administration for Trogarzo® (ibalizumab-uiyk), a monoclonal antibody antiretroviral therapy (ART) for the treatment of heavily treatment-experienced adults with multidrug-resistant (MDR) HIV-1 infection failing their current antiretroviral regimen.
The TMB-302 study, conducted in partnership with TaiMed Biologics, enrolled 21 subjects (7 HIV-positive and 14 HIV-negative) to assess the pharmacokinetics, efficacy, and safety of IM administration of Trogarzo® as compared to intravenous (IV) infusion.
Mean Trogarzo® trough concentrations were greater than 15 µg/mL, suggesting that IM injection was sufficient at maintaining the drug trough concentration above the therapeutic level of 0.3 µg/mL. The mean trough concentrations were comparable between IV infusion and IM injection in HIV-positive subjects. However, the primary endpoint measuring a 90% confidence interval of the ratio of IM injection to IV infusion (0.69, 1.08) did not meet the equivalence limits (0.8, 1.25). Viral suppression, a key secondary clinical endpoint, was maintained in all HIV-positive subjects throughout the IM phase and the overall study.
Each study subject received IM maintenance doses for eight weeks of treatment and a total of 152 IM injections were administered, which were well tolerated. One subject reported injection-site pruritus (itching) at a single time point, and no subjects reported injection-site pain when Trogarzo® was administered intramuscularly.
With the TMB-302 data in hand, Theratechnologies is seeking expert advice prior to completing a regulatory submission of the Trogarzo® IM administration maintenance dose to the U.S. Food and Drug Administration (FDA). The FDA is currently reviewing the Company’s submission for the loading dose of the Trogarzo® IV push method of administration and a decision is expected in mid-December.
About Trogarzo® (ibalizumab-uiyk)
Trogarzo® (ibalizumab-uiyk) is a long-acting, CD4-directed, post-attachment HIV-1 inhibitor. In the United States, Trogarzo®, in combination with other antiretroviral(s), is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in heavily treatment-experienced adults with multidrug-resistant HIV-1 infection failing their current antiretroviral regimen. Trogarzo® is not approved in Canada.
Trogarzo® is administered by intravenous infusion as a single loading dose of 2,000 mg followed by a maintenance dose of 800 mg every two weeks after dilution in 250 mL of 0.9% Sodium Chloride Injection, USP. In October 2022, the Trogarzo® maintenance dose was approved by the FDA to also be administered as an undiluted IV push over 30 seconds.
Important Safety Information
Do not receive Trogarzo® if you have had an allergic reaction to Trogarzo® or any of the ingredients in Trogarzo®. Trogarzo® can cause allergic reactions, including serious reactions, during and after infusion. Tell your healthcare provider or nurse, or get medical help right away if you experience any symptoms of an allergic reaction. Before you receive Trogarzo®, tell your healthcare provider about all of your medical conditions, including if you are pregnant or plan to become pregnant as it is not known if Trogarzo® may harm your unborn baby, or if you are breastfeeding or plan to breastfeed as it is not known if Trogarzo® passes into breast milk. Tell your healthcare provider about all the medicines you take, including all prescription and over-the-counter medicines, vitamins, and herbal supplements.
Changes in your immune system (immune reconstitution inflammatory syndrome) can happen when you start taking HIV-1 medicines. Your immune system might get stronger and begin to fight infections that have been hidden in your body for a long time. Tell your healthcare provider right away if you start having new symptoms after starting your HIV-1 medicine. The most common side effects of Trogarzo® include diarrhea, dizziness, nausea, and rash. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Trogarzo®. For more information, ask your healthcare provider or pharmacist.
Full prescribing information is available at www.trogarzo.com.
Theratechnologies (TSX: TH) (NASDAQ: THTX) is a biopharmaceutical company focused on the development and commercialization of innovative therapies addressing unmet medical needs. Further information about Theratechnologies is available on the Company's website at www.theratech.com, on SEDAR at www.sedarplus.ca, and on EDGAR at www.sec.gov. Follow Theratechnologies on Linkedin and Twitter.
This press release contains forward-looking statements and forward-looking information (collectively, the “Forward-Looking Statements”), within the meaning of applicable securities laws, that are based on our management’s beliefs and assumptions and on information currently available to our management. You can identify Forward-Looking Statements by terms such as "may", "will", "should", "could", “promising”, “would”, "outlook", "believe", "plan", "envisage", "anticipate", "expect" and "estimate", or the negatives of these terms, or variations of them. The Forward-Looking Statements contained in this press release include, but are not limited to, statements regarding the completion of a regulatory submission of the Trogarzo® IM administration maintenance dose with the FDA and the timelines about expected decision of the FDA on the Company’s submission for the IV push method of administration of the Trogarzo® loading dose. Certain assumptions made in preparing the Forward-Looking Statements include that: we will file the regulatory submission of the Trogarzo® IM administration maintenance dose with the FDA in the last calendar quarter of 2023; the FDA will approve the IM administration of Trogarzo® option for the maintenance dose and the IV push method of administration of the Trogarzo® loading dose; sales of Trogarzo® will increase with the addition of those two methods of administration; and Trogarzo® will continue being reimbursed by private and public payors. Forward-Looking Statements are subject to a number of risks and uncertainties, many of which are beyond Theratechnologies’ control that could cause actual results to differ materially from those that are disclosed in or implied by such Forward-Looking Statements. These risks and uncertainties include, but are not limited to, those related to or arising from: a delay in the filing of the regulatory submission of the Trogarzo® IM administration maintenance dose to the FDA; the non-filing of the IM administration maintenance dose of Trogarzo® with the FDA if experts recommend against it; the non-approval by the FDA of the Trogarzo® IM administration maintenance dose and/or the IV push method of administration of the Trogarzo® loading dose; and, sales of Trogarzo® do not increase despite the approval by the FDA of both or any one of those new methods of administration of Trogarzo® . We refer current and potential investors to the “Risk Factors” section of our Annual Information Form dated February 27, 2023, available on SEDAR at www.sedarplus.ca and on EDGAR at www.sec.gov as an exhibit to our report on Form 40-F dated February 28, 2023, under Theratechnologies’ public filings for additional risks involved in our business. The reader is cautioned to consider these and other risks and uncertainties carefully and not to put undue reliance on Forward-Looking Statements. Forward-Looking Statements reflect current expectations regarding future events and speak only as of the date of this press release and represent our expectations as of that date. We undertake no obligation to update or revise the information contained in this press release, whether as a result of new information, future events or circumstances or otherwise, except as may be required by applicable law.
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