A perfect key to success by these 8006 free pdf

If you really to show your professionalism so just Passing the 8006 exam is not sufficient. You should have enough Exam I: Finance Theory- Financial Instruments- Financial Markets knowledge that will help you work in real world scenarios. Killexams.com specially focus to improve your knowledge about 8006 objectives so that you not only pass the exam, but really get ready to work in practical environment as a professional.

Exam Code: 8006 Practice exam 2023 by Killexams.com team
8006 exam I: Finance Theory, Financial Instruments, Financial Markets

Exam Details for 8006 exam I: Finance Theory, Financial Instruments, Financial Markets:

Number of Questions: The exam consists of multiple-choice questions, with a total of approximately 90 questions.

Time Limit: The total time allocated for the exam is 3 hours.

Passing Score: The passing score for the exam varies and is determined by the certifying body or organization offering the exam.

Exam Format: The exam is typically conducted in a proctored environment, either in-person or online.

Course Outline:

1. Finance Theory:
- Time value of money and discounted cash flow analysis
- Risk and return concepts
- Capital budgeting and investment decision-making
- Cost of capital and capital structure theories

2. Financial Instruments:
- Equity instruments (stocks and shares)
- Debt instruments (bonds and fixed income securities)
- Derivatives (options, futures, swaps)
- Alternative investments (private equity, hedge funds, real estate)

3. Financial Markets:
- Types of financial markets (money market, capital market)
- Primary and secondary markets
- Market efficiency and market anomalies
- Market participants and their roles (investors, issuers, intermediaries)

Exam Objectives:

1. Understand the foundational principles and concepts of finance theory.
2. Demonstrate knowledge of different financial instruments and their characteristics.
3. Understand the functioning and structure of financial markets.
4. Apply financial theory and concepts to practical scenarios and decision-making.

Exam Syllabus:

The exam syllabus covers the following topics:

1. Finance Theory
- Time value of money
- Risk and return
- Capital budgeting
- Cost of capital and capital structure

2. Financial Instruments
- Equity instruments
- Debt instruments
- Derivatives
- Alternative investments

3. Financial Markets
- Types of financial markets
- Primary and secondary markets
- Market efficiency
- Market participants

Exam I: Finance Theory, Financial Instruments, Financial Markets
PRMIA Instruments, certification
Killexams : PRMIA Instruments, certification - BingNews https://killexams.com/pass4sure/exam-detail/8006 Search results Killexams : PRMIA Instruments, certification - BingNews https://killexams.com/pass4sure/exam-detail/8006 https://killexams.com/exam_list/PRMIA Killexams : ATP Certificate

All airline pilots in the United States are required to hold an airline transport pilot certificate. To obtain this certificate, applicants must have at least 1,500 flight hours, 200 cross-country hours, completed instrument rating and have a commercial certificate. 

Saint Louis University has been granted approval to provide a transcript endorsement certifying graduates for a 250-hour or 500-hour reduction towards the ATP certificate for the Bachelor of Science in aeronautics degree with a concentration in flight science or aviation management. This allows you to qualify for the ATP certification at the age of 21 instead of 23.

You must complete 30 credits of approved coursework to be eligible for the 250-hour reduction or complete 60 credits of approved coursework to be eligible for the 500-hour reduction.

To obtain a certifying transcript endorsement, submit the Reduced ATP Minimums application. Once the application is received, the following information will be verified:

  • Your graduation from Saint Louis University with a concentration in aviation management or flight science.
  • Your accumulation of approved credits in approved courses.
  • Your completion of the commercial or instrument certification at SLU.

If approved, a certifying endorsement will be applied to your transcript consistent with Saint Louis University’s letter of authorization. Allow at least two to three weeks for submission.

You will need to request an official transcript to include with the FAA Form 8710-1 when taking the airline transport-restricted practical test.

What Saint Louis University degrees are approved by the FAA?

Our Bachelor of Science in Aeronautics degree with a concentration in flight science and aviation management are approved by the FAA. For students who graduated prior to 2009, the Bachelor of Science in aeronautics degree with a concentration in aviation science or professional pilot is also approved by the FAA.

What courses has SLU received approval for under the Institutional Authority program?

The following Saint Louis University courses are approved under the Institutional Authority Program:

  • ASCI 1020: Intro to ATC Systems
  • ASCI 1850: Safety Management Systems
  • ASCI 2020: ATC Operations and Procedures
  • ASCI 2200: Concepts in Aerodynamics
  • ASCI 3010: Jet Transport Systems I
  • ASCI 3020: Jet Transport Systems II
  • ASCI 3060: Turbine Aircraft Transition
  • ASCI 3100: Air Carrier Operations
  • ASCI 4010: Jet Flying Techniques I
  • ASCI 4020: Jet Flying Techniques II
  • ASCI 4050: Human Factors
  • ASCI 4250: Professional. Ethics and Standards
  • ASCI 4350: Team Resource Management
  • FSCI 1150: Flight I
  • FSCI 1250: Basic Flight Foundations
  • FSCI 1300: Aviation Weather
  • FSCI 1550: Flight 2
  • FSCI 1560: Flight 2 Transition
  • FSCI 2150: Flight 3
  • FSCI 2250: Instrument Flight Foundations
  • FSCI 2550: Flight 4
  • FSCI 2650: Navigation Foundations
  • FSCI 2750: Accident Investigation
  • FSCI 3550: Flight 5
  • FSCI 3062: Turbine Aircraft Transition
  • FSCI 4012: Jet Flying Techniques I
  • FSCI 4013: Jet Flying Techniques I Laboratory
  • FSCI 4022: Jet Flying Techniques II
  • FSCI 4023: Jet Flying Techniques II Laboratory
  • FSCI 4450: Aviation Law
  • PHYS 1350: Aviation Physics
  • PSY 1010: General Psychology
How do I know if I qualify for the ATP reduced minimums certifying statement?

In order to qualify for the certifying statement on your transcript, you must complete your instrument and commercial ratings at Saint Louis University, graduate with a Bachelor of Science degree in aeronautics with a concentration in flight science or aviation management, and complete at least 30 or 60 hours of approved coursework. Students who complete at least 30 hours of approved coursework are eligible to receive the 1,250-hour endorsement. Students who complete at least 60 hours of approved coursework are eligible to receive the 1,000-hour endorsement.

If I transferred to SLU, will my transfer coursework apply to the 30 and 60-hour requirements?

In order for transfer credits to be eligible towards the 30 and 60-hour requirements, they must have been completed at an approved institution that holds approval for the transferred coursework and must have been completed while you were enrolled in that school’s approved aviation degree program. Prior to us accepting transfer credit for inclusion, acceptable documentation of completion and eligibility of the coursework under the Institutional Authority program must be presented to the aviation department.

Tue, 13 Jun 2023 09:52:00 -0500 en text/html https://www.slu.edu/science-and-engineering/academics/parks-aviation-science/flight-school/atp-certificate.php
Killexams : Chapter 11: Training Instruments and Tools No result found, try new keyword!A training instrument differs from a test in that the answers to the questions are not considered right or wrong . Many of the instruments included here are assessments and self-assessments - ... Mon, 19 Feb 2018 09:24:00 -0600 en-US text/html https://www.globalspec.com/reference/23912/203279/html-head-chapter-11-training-instruments-and-tools Killexams : Saint Louis University Flight School

 Saint Louis University's Flight School trains students to become skilled pilots as well as strong industry leaders. 

Students enrolled in Saint Louis University's aviation program are able to fly within weeks of their freshman year, and continuously gather more and more certification throughout each year of the flight science degree program.

FAA Medical Certificate Requirements for Flight Training

All students planning to begin flight training at Saint Louis University are advised to hold a current Federal Aviation Administration (FAA) medical certificate. Proof of your holding a current first or second-class medical certificate must be provided before you will be allowed to enroll in any flight training courses. A medical certificate will be considered current if it has been issued within 12 calendar months prior to the start of flight training.

Without a current FAA second-class or first-class medical certificate, you will not be allowed to enroll in any flight training course offered by Saint Louis University.

Learn More About FAA Medical Certificate Requirements

Location and Transportation

Our Center for Aviation Science is housed at the St. Louis Downtown Airport, located at 4300 Vector Drive in Cahokia, Illinois, and can be reached at 314-977-9569.

University transportation between campus and the Center for Aviation Science is available for aviation students during the fall and spring semesters.

  • A Center for Aviation Science shuttle operates hourly Monday through Friday from 7 am to 5 p.m.  The shuttle pick-up and drop-off point is located at Grand Hall on the Saint Louis University campus and at the Center for Aviation Science at the St. Louis Downtown Airport.
  • Additional transportation is available during off hours and on weekends via SLU Ride. Students are to use the TapRide app (which can be downloaded from the Apple App Store or Google Play) during the hours of operation to request a ride.
  • Outside of SLU Ride and the shuttle hours, the Department of Public Safety can provide safety escorts. To request a safety escort, call 314-977-3000.

Saint Louis University Aircraft Fleet and Technology

SLU hosts a versatile aircraft fleet, including these cutting-edge airplane options:

Diamond DA-20

Our GPS-equipped Diamond DA-20 aircraft, capable of flight under Instrument Flight Rules (IFR), are used for primary and instrument training. The Diamond DA-20 is a two-seat, all composite airplane that is ideal for high-utilization flight instruction environments and has an industry-leading safety record and outstanding fuel economy.

Piper Archer PA-28-181 with Garmin G1000NXi

The technologically advanced Piper PA-28-281 is equipped with a glass cockpit, Garmin G1000 NXi avionics and autopilot, allowing you to receive additional training in an aircraft with electronic systems that are typical of today’s commercial aircraft.

Seminole PA44

The multi-engine, advanced-training Seminole is sleek, strong, consistent and smart. Powerful twin 180-horsepower Lycoming engines make Seminole the only true multi-engine trainer available today, providing a unique and vital advanced instrument training experience. Its simplicity, stability and safety have made it a low-maintenance, high-value mainstay of training programs everywhere.

Flight training is further supported by our fleet of Frasca advanced aircraft training devices (AATD), also referred to as simulators.

Our smaller class sizes and individual flight instruction ensure a student-centered approach to learning and the individualized attention afforded by a private education. 


You can register for flight courses at Saint Louis University as soon as you are admitted to the flight science concentration.

To register for a flight school course, coordinate with the chief flight instructor for a flight slot. Once a flight slot has been obtained, you may register with the consent of your faculty mentor and academic advisor. You must register for flight courses online. New students may obtain a flight slot and register for their flight course during SLU 101.

Students are not allowed to register for a department flight course without having completed prerequisite coursework unless they have consent from the Department of Aviation Science. To complete the degree requirements in four years, it’s important that you continue to make adequate progress in each flight course.

Currently required FAA records are maintained using the Talon Systems’ Education and Training Administration software. Upon enrollment in a flight course, you will receive access to your flight training records via your ETA login. You are encouraged to monitor your flight training progress to avoid or anticipate additional flight course charges.

Tue, 13 Jun 2023 09:52:00 -0500 en text/html https://www.slu.edu/science-and-engineering/academics/parks-aviation-science/flight-school/index.php
Killexams : Instruments / Sensors Certification Services No result found, try new keyword!Company Information: Edgetech Instruments services all brands of hygrometers with ... assuring the highest level of accuracy and confidence. Certification Level: Products; Quality / Management Systems ... Mon, 12 Feb 2018 23:35:00 -0600 en-US text/html https://www.globalspec.com/ds/3461/areaspec/products_instrument_sensors Killexams : Purdue Imaging Facility

The Purdue Imaging Facility (PIF) is a research resource for Purdue faculty/staff/students and other academics and non-academics who want access to state-of-the-art light microscopy for their research and development work. PIF specializes in Confocal and Multi-Photon Microscopy, Pre-clinical Bioluminescence/Fluorescence and Computed Tomography. In addition, we are a resource for researchers at Purdue University and biotech companies around the community. PIF is a member of the Indiana CTSI service core community. We provide the instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project-specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available as our knowledge base permits. Collaborations and contract research services are encouraged.


Confocal microscopy

Our facility provides three visible-wavelength laser point scanning confocal systems suitable for creating multi-dimensional images of living or non-living samples.

  • Multi-colored fluorescence imaging
  • Photoablation/photoactivation
  • Imaging in aqueous environments
  • Material science – fluorescence and reflectance


Multiphoton microscopy

If your sample is thicker than 100 µm or you require less phototoxicity to your living sample, you might benefit by using a multi-photon (MP)

  • Multi-dimensional images of thick samples, up to 800 microns
  • Live cell and live animal (intravital) imaging
  • Photo-uncaging
  • Photoablation/photoactivation
  • Second Harmonic Generation (non-centrosomatic)

TIRF microscopy

Total Internal Reflection Fluorescence uses a finite wave-front of energy to fluorescently illuminate samples and limit excitation of fluorophores close to the coverslip to dramatically increase the signal to noise of your sample.  

  • Protein dynamic studies on the cell membrane
  • Single molecule examinations

Super Resolution microscopy

For spatial resolution beyond the diffraction-limit (<220 nm) we offer Super Resolution microscopy with both SIM (3 colors) and STORM.

  • Very high resolution intracellular imaging in thin samples
  • Detailed localization analysis

Wide-Field imaging

  • Cell morphology
  • Immunohistochemistry
  • Polarization
  • Amyloid assays

Pre-Clinical Molecular and microCT

The Bindley Imaging Facility provides systems capable of imaging larger subjects such as small rodents, medical devices or other non-biologics

  • Small Animal CT Imaging
  • Material science - Computed Tomography 
  • Fluorescent and Bioluminescent Imaging

Image Processing and analysis for all data

Images are great to display but have so much more data. Use one of our commerical analysis software tools to pull out all the information.

  • Co-localization analysis
  • Intensity analysis
  • Time-lapse imaging of dynamic intracellular events
  • Three-dimensional morphology
  • Deconvolution
Sat, 04 Jun 2016 08:32:00 -0500 en text/html https://www.purdue.edu/discoverypark/bioscience/facilities/core/bioscience/index.php
Killexams : Lon Hemphill
Lon Hemphill began his career in the field of instrumentation in the army as a navigation equipment repairman. After 3 years in the army, he returned to his former job at the Joliet Army Ammunition Plant in Joliet, Illinois and transferred into the instrument department. The ammunition plant made their own acid, which was used to make TNT [ Tri Nitrated Toluene], and poured the TNT into the bomb casings. After 6 years there, he got a job in the instrument department at Honeywell in Metropolis, Illinois [ his home town]. Honeywell in Metropolis processes Uranium ore into UF6 [ Uranium Hexafluoride ] , the first step in the manufacturing of nuclear fuel rods for nuclear power plants. After 26 years at Honeywell as an instrument technician, he retired at age 54. Since that time he worked for Air Products in Calvert City, Kentucky as a replacement instrument technician for employees on medical leave and during shutdowns. He is presently working for Collier Associates contracted as an instrument designer at Honeywell in Metropolis to convert their 50 year old control system to DCS [ Distributive Control System] control.

Lon graduated high school in 1965. He received his electronics training in the army. He has taken any instrument training available whether by a manufacturers association at a local college or training offered by his employer. He has taken correspondence courses in industrial electronics and industrial instrumentation [ about 3 years each ]. By going to night school, he got his associates degree in 1973. About 5 years before he retired, he thought it would be a good thing if he could transfer what he had learned over the last 30 years to people new to the field of instrumentation, so they could build on what he had learned, and become  much better than he could ever hope to have been. So, he started going to night school and received a Bachelor of Science Degree in Workforce Education and Development from Southern Illinois University in 1998. Since his retirement from Honeywell in 2001, he has been a substitute high school teacher for the state of Illinois. He also worked for Multi-Skills Training of Murray, Kentucky teaching instrumentation at Murray State University and onsite at Vanderbilt Chemical. He is certified by ISA as a CCST [ Certified Control System Technician ] Level III.

Fri, 05 Nov 2021 23:35:00 -0500 en text/html https://www.isa.org/training/instructor/lon-hemphill
Killexams : Pricey training complicates US pilot diversity push No result found, try new keyword!Blanco recently attained instrument certification, a second major stepping-stone after the private pilot license. She hopes to work as a flight instructor at Farmingdale after graduating ... Sat, 06 May 2023 13:23:00 -0500 en-us text/html https://www.msn.com/ Killexams : Internal Users

Faculty Account Application

To open a Core Research Facilities (CRF) Faculty account, complete and submit the account application. Please supply all requested information.

  • Please list your name as the account name.
  • Do not list your account as UMass Lowell or your department.
  • Since the application form is able to accommodate external users as well please use the “automatic fill buttons” to complete the fields requesting billing and signatory official information.
  • Please supply an account passphrase on your application. The passphrase is assigned by you, the account holder to safeguard your account.

Upon electronic receipt of your application you will be issued a CRF account number. The account number and passphrase will be emailed to you. Please forward this information to students authorized to use your account in order for them to apply for user registration. A user account is automatically generated person completing the account application form.

User Registration

Once CRF Account is established, students authorized to use the account may register for a user id. Users are required to provide the faculty CRF account number and passphrase on the user registration form.

Users are required to create a password for their login credentials. The password needs to be at least 8 characters. This password is encrypted and unreadable by anyone. Please email: crf@uml.edu to have your password reset.

User Rates

Internal user rates are direct cost based upon a cost recovery model in accordance with government guidelines. Industry rates are posted on the Core Research Facilities website. Internal rates, industry partners, academic and government rates are viewable upon users login to the CRF reservation system. Core Research Facilities are subsidized by UMass Lowell. The UMass Lowell subsidy is applied in our cost model prior to determining the direct cost allocation in our billing rates.

Rates include lab supplies*, stock materials, short use of the research laboratory ancillary and equipment and tools.

In accordance with federal guidelines CRF user rates are reviewed on an annual basis to coincide with the University’s fiscal year. Published rates will be reviewed and possibly adjusted July 1 of each fiscal year.

Note 1: Once users are certified, lab staff will provide minimal guidance (less than 10 minutes for each occurrence free of charge) for sample preparation, etc. Users requiring sample preparation must reserve “sample prep services” from the order menu.

Note 2* (Rates for the Nanofabrication Laboratory include gowning for one person. Gowning for additional guests must be ordered as an additional line item on the ordering system). Users of the experimental bays are required to prepay any and all related equipment installation and removal cost.

Safety Training

All “self-use” instrument users must complete Level 1(UMass Lowell General Training and Level 2 (lab specific safety training) prior to lab entry. Level 1 safety training may be completed online on the Life Safety & Emergency Management website.

Level 2 safety training is to be coordinated with the specific Lab Director/Manager. There is no charge for safety training.


  • There is no charge for general lab and safety training.
  • Registered CRF users are required to complete training on instruments and be approved by the Lab Manager before registering for self-use. Users should schedule training close to when self-use will start. If there is a lapse of six (6) or more months between training and usage, users are required to re-train on the instrument.
  • Instrument training rate is the combined rate of the hourly self-use rate use plus the blended bill-out labor rate.
  • Instrument SOPs and related documents are available on the instrument listing.

Operating Hours

Standard operating hours for internal users are 8:30 a.m. until 5 p.m., or as permitted by the specific CRF lab director/manager. The Nanofabrication Lab operates on a 7 a.m. - 7 p.m. schedule.

Instrument use outside standard hours may be coordinated with the lab director/manager. After hours use of any CRF is not permitted without the approval of the lab manager/director.

Orders & Reservations

Our CRISP ™ database provides streamline searches, and order placement and reservations. Using the calendars feature, users may request services (referred to as “assisted use”) to be fulfilled by our lab staff. For such orders, please designate a required due date. When reserving using “self-use” hours, users request a specific time slots for instruments and facilities use. The scheduling tool will inform users when there is a conflict in placing the reservation. Please do not make reservation when there is a schedule conflict with another user. Reservations may be made for all CRF using one order form. Shopping carts remain open in the order system until orders are submitted. Users may use the “notes” feature of the order form to communicate information or ask question of the lab directors/managers.

All order are reviewed and confirmed by the appropriate CRF lab directors/managers. Users will receive an email order confirmation. Order confirmation should be received within 8 business hours of the order request.

Upon completion of an order, CRF lab staff close the order in the CRISP™ database system. If for any reason you are not satisfied with the instruments performance or services rendered, please discuss with the specific CRF lab director/manager.

A 24-hour cancellation policy is requested. Lab Director/Managers have the discretion to require a stricter cancellation policy based upon CRF activity. Users will be billed for “no-shows.” Charges for “no-shows” may not be charged to government sponsored programs and will be charged to faculty discretionary accounts.

SPEED TYPE NUMBERS are required at the time of order. We request that faculty provide their students with the correct speed type number to include on the CRF order. Faculty may email the CRF Business Office with the appropriate speed type number once the billing statement is received. After 30 days if faculty are non-responsive to request for the appropriate charge number, CRF invoices will be charged to the faculty’s discretionary account. Core Research Facilities Agreement may be indicated under the “billing reference” field on the order form.

Use Types

  • Assisted: Assisted use is a service provided by the Core Research Facility. Our professionally trained staff will operate the reserved instrument and provide the data obtained to the user. When a more extensive analysis interpretation or expertise is required, users are to reserve “Lab Staff Analysis and Service” time in addition to instrument time.
  • Training: All self-user are required to complete the prescribed training requirements listed in the description field for each instrument. Users with experience using an instrument must receive a training waiver and prove competency to the appropriate lab director/manager.
  • Self-use: Certified users may reserve instrument use time. NOTE: Once users are certified, lab staff will provide minimal guidance (less than 15 minutes for each occurrence) for sample preparation, etc. Users requiring sample preparation must reserve “sample prep services” from the order menu.

Billing Statements and Payments

  • Billing statements are compiled by all orders for each Core Research Facility.
  • Monthly billing statements are emailed to faculty as well as a pdf copy of the invoice,
  • Billing statements will reflect all orders for the monthly period. Please provide omitted speed type numbers to the CRF Business Office upon receipt of billing statement.
  • The CRF Business Office submits the corresponding journal entry transmittal form to the Bursar’s Office for processing. After 30 days if faculty are non-responsive to requests for the appropriate charge number, CRF invoices will be charged to the faculty’s discretionary account.
Wed, 30 Mar 2016 11:14:00 -0500 en text/html https://www.uml.edu/Research/CRF/Introduction/internal-users.aspx
Killexams : Pa. guitar company first in U.S. to get plastic-free sustainability certification for instrument

A prominent Pennsylvania guitar maker is the first manufacturer in the country to receive an environmental sustainability certification for one of its instruments.

C.F. Martin & Company announced Thursday that it has received the Preferred by Nature Sustainability Framework certification, making it the first company in the United States to do so, and only the second worldwide.

According to a release, the Nazareth-based manufacturer received the accolade for its Martin OM Biosphere guitar, which was designed to show the company’s support for the preservation and replenishment of coral reefs.

The company called reefs "some of the most diverse and valuable ecosystems on earth," and said the instrument is "a call to action on climate change."

Preferred by Nature is a nonprofit supporting better land management and business practices with a focus on land use, primarily through forest, agriculture and climate impact commodities, and related sectors like tourism and ecosystem restoration.

The nonprofit’s Sustainability Framework aims to guide organizations toward sustainable practices, and includes four main elements: management and business, people, nature, and climate.

"By adhering to the Sustainability Framework, companies demonstrate their commitment to responsible resource management, human rights, and nature conservation, contributing to a more sustainable and equitable future," the release said.

“Preferred by Nature and Martin share the same vision: ‘To pass on the Earth to coming generations in a good shape, we must urgently invent and adopt more sustainable ways of living, sourcing and trading.’” Cindy McAllister, Martin Director of Intellectual Property, Community, and Government Relations, said in a statement.

The OM Biosphere is 100% FSC-certified, a label given by the Forest Stewardship Council which indicates that the product's materials came from sustainable and responsibly-managed forests.

It is the second plastic-free guitar in production, following the now-discontinued 00L Earth guitar, introduced in 2021 and also made by Martin.

A guitar with the sun rising over Earth as viewed from space depicted on the body.



C.F. Martin & Company

The Martin 00L Earth guitar.

The company said at the time that it chose to go plastic-free with the 00L Earth because of the harm single-use plastics are causing to ecosystems, and its contributions to global warming.

The OM Biosphere costs $2,299, and its design features a sea turtle and colorful ocean reef scene created by artist Robert Goetzl, who also designed the Earth-and-stars design used on the 00L Earth.

It also includes a sustainable gig bag made of hemp, which Martin said is another company first.

Having received the Preferred by Nature certification, the OM Biosphere will carry the nonprofit's Hummingbird Seal, which the release says, “combines both sustainability aspects and climate requirements” and “signifies adherence to stringent sustainability criteria.”

These include compliance with the framework's principles, as well as required carbon compensation and offsetting measures to mitigate environmental impacts.

Read more from our partners, WDIY.

Sun, 20 Aug 2023 19:10:00 -0500 en text/html https://www.wesa.fm/arts-sports-culture/2023-08-20/c-f-martin-guitar-plastic-free-sustainability-pennsylvania
Killexams : Mass Spectrometry

Please note that all work performed in BC core facilities and recharge centers should always be appropriately acknowledged.  If you are publishing or presenting data acquired in BC core facilities and recharge centers, please include the following statement in the Acknowledgement section of your manuscript/poster/presentation, "The authors would like to thank the Boston College <insert facility name> for assistance with the work presented in this paper/poster/presentation*."
* Delete as appropriate

Complete Facility Description

1. Advion Expression CMS

TThe expression CMS is a single quadrupole mass spectrometer, equipped with ESI and APCI probes, switchable with minimal effort.

The instrument has a mass range of m/z 10 to m/z 1,200, and a resolution of 0.5-0.7 m/z, units at 1000 m/z, over the entire acquisition range.

In Full scan mode the CMS has sensitivity for Reserpine of 100pg and in SIM mode of 10pg, with a 5μl sample injection volume of 100μl/min.


The JEOL AccuTOF, configured with a new Direct Analysis in Real Time (DART) ion source, represents a significant breakthrough in mass spectrometry. It is the first mass spectrometer to allow the analysis of solids, liquids and gaseous samples at atmospheric pressure and ground potential by simply placing the sample between the DART and the mass spectrometer. No solvents or sample preparation are required. The system design results in high throughput with no carry over, even with neat polyethylene glycol (PEG). The DART can even analyze samples directly from a variety of surfaces such as concrete, currency, food, pills, clothing, and TLC plates. The AccuTOF DART combination achieves high specificity through high resolution. Exact mass measurements together with precise isotopic abundances can rapidly identify unknown compounds by their elemental compositions.

The DART ion source is based on the reactions of excited-state species with reagent molecules and polar or non-polar analytes. It is free of the limitations that are common to other atmospheric pressure ion sources, which require direct exposure of gaseous or vaporized liquid samples to elevated temperatures and electrical potentials, ultraviolet irradiation, laser radiation, or a high-velocity gas stream. DART does not alter the sample in any way, nor does it expose the user to a potentially harmful substance or dangerous situation.

DART Applications

3. Agilent 6220 Time-of-Flight LC/MS

The Agilent 6220 TOF LC/MS delivers exceptional analytical performance, including 2-ppm mass accuracy, and is ideal for protein and metabolite profiling. The powerful combination of resolving power and high mass accuracy allows identification of impurities in complex matrices faster and with greater confidence than with other methods. The instrument has a variety of ion source ESI, APCI, APPI and AP-MALDI meeting the widest range of applications.

The atmospheric pressure photoionization (APPI) source is especially useful for analyzing compounds that ionize poorly by ESI and APCI. It uses a krypton lamp that emits photons at energy levels high enough to ionize compounds with a UV chromophore, but low enough to minimize the ionization of air and common HPLC solvents. Relatively low ionization energy means the APPI source causes minimal fragmentation and generates mostly molecular ions and protonated molecules.

The atmospheric pressure matrix assisted laser desorption ionization (AP-MALDI) source provides fast, easy, and ultrasensitive analysis for samples that do not need online separation. It is ideal for protein identification and confirmation using peptide mass fingerprinting (PMF).

Coupled to the mass spectrometer, a 1200 series rapid resolution LC system offers a unique combination of flexibility, resolution and speed. Benefits include the ability to run both rapid resolution and conventional HPLC methods on the same chromatography system, which supports both standard and narrow bore columns. Rapid resolution, in turn, offers up to 60% higher resolution than conventional HPLC, with approximately 20 times faster analysis time, compared to standard HPLC.

4. Agilent 6460 Triple Quad

The 6460 Triple Quad MS is a liquid chromatograph triple quadrupole mass spectrometer that performs MS/MS using three sets of parallel rods (in this case, quadrupole, hexapole, quadrupole). The first quadrupole separates ions into precursor ions that are fragmented in the hexapole into product ions, which are separated by the second quadrupole. Often, two or more precursor ions and their product ions are monitored in sequence in MRM (multiple reaction monitoring) mode. You can monitor up to 4000 MRM transitions by using Dynamic MRM.


Mass spectrometry instrument training request procedure:

Currently, after completing the required training users will have access to the JEOL AccuTOF DART and Bruker MALDI systems.  Training requests can and should be initiated via iLabs, in order to arrange a suitable date and time for training to be carried out.  This is followed by a period of supervised instrument time before any access is granted for off hours works.

Thu, 13 Aug 2020 11:17:00 -0500 en text/html https://www.bc.edu/bc-web/research/sites/vice-provost-for-research/about/research-facilities/mass-spec.html
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